Profiles of psychiatric disorders among heroin dependent individuals in Changsha, China.
Profiles of psychiatric disorders among heroin dependent individuals in Changsha, China.
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DOI：
10.1016/j.drugalcdep.2015.01.028
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发表时间：
2015-04-01
影响因子：
4.2
通讯作者：
Hao W
中科院分区：
文献类型：
--
作者：
Yang M;Liao Y;Wang Q;Chawarski MC;Hao W
精神疾病和物质使用障碍的强共病性在中国境外已有充分的文献记录，但尚未在中国的药物使用个体中进行广泛研究。本研究评估了中国长沙地区海洛因依赖者中精神疾病和物质使用障碍的共病模式。研究对象为2008年3月10日至2008年10月30日期间连续入住长沙市两所强制戒毒所和一所自愿戒毒所的戒毒人员1002人。使用了DSM-IV-TR轴I障碍患者版结构化临床访谈（SCID-I/P）和DSM-IV-TR轴II人格障碍结构化临床访谈（SCID-II）。精神健康障碍在研究参与者中非常普遍：29.6%的人一生中至少有一次DSM-IV轴I，19.5%的人至少有一次当前（过去一个月）轴I精神健康障碍。反社会（40.7%）和边缘型（22.6%）人格障碍是最常见的DSM-IV轴II终身诊断，情绪障碍（19.1%）是最常见的轴I终身障碍; 57.8%的人除了阿片类药物依赖外还有其他物质使用障碍。研究结果表明，义务教育环境中的女性社会经济地位低于义务教育环境中的男性，而义务教育环境中的男性患有包括人格、情绪障碍、药物使用共病在内的共病的比率高于自愿环境中的男性，社会经济地位也低于自愿环境中的男性。研究结果表明，迫切需要扩大和提高中国强制康复机构的诊断和治疗能力，并需要专门针对女性康复者的额外服务和干预措施。
The strong comorbidity of psychiatric and substance use disorders is well documented outside of China, however it has not been studied extensively among drug using individuals in China. This study evaluated patterns of co-occurring psychiatric and substance use disorders among heroin dependent individuals in Changsha, China. Participants were 1002 individuals consecutively admitted between March 10 and October 30, 2008 into two compulsory and one voluntary drug rehabilitation centers in Changsha. The Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition (SCID-I/P) and the Structured Clinical Interview for DSM-IV-TR Axis II personality Disorders (SCID-II) were used. Mental health disorders were highly prevalent among study participants: 29.6% had at least one lifetime DSM-IV Axis I and 19.5% had at least one current (past month) Axis I mental health disorder. Antisocial (40.7%) and Borderline (22.6%) Personality Disorders were most prevalent DSM-IV Axis II lifetime diagnoses and a mood disorder (19.1%) was the most prevalent Axis I lifetime disorder; 57.8% had other substance use disorder in addition to opioid dependence. Study results indicate that females in compulsory settings have lower socio-economic status than males in compulsory settings, and that males in compulsory settings have higher rates of co-morbidities, including personality, mood disorders, substance use co-morbidities, and lower socio-economic status than males in the voluntary setting. The study findings suggest an urgent need to expand and improve diagnostic and treatment capabilities in compulsory rehabilitation settings in China and a need for additional services and interventions specific for female rehabilitants.