Individual differences in self-regulatory failure and menstrual dysfunction predict upper respiratory infection symptoms and antibody response to flu immunization.
Individual differences in self-regulatory failure and menstrual dysfunction predict upper respiratory infection symptoms and antibody response to flu immunization.
复制标题
自我调节失败和月经功能障碍的个体差异可以预测上呼吸道感染症状和流感免疫的抗体反应。
DOI：
10.1016/j.bbi.2008.01.004
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Kwapil,Lori
中科院分区：
文献类型：
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作者：
Strauman,TimothyJ;Coe,ChristopherL;McCrudden,MeganC;Vieth,AngelaZ;Kwapil,Lori
先前的研究表明，激活个人目标的认知启动操作会急剧增加或减少自然杀伤细胞的细胞毒性，这取决于个人是否认为自己正在朝着目标前进。在实验室环境中的这些发现揭示了一种心理生物学途径，即失败的经历可以影响健康，但没有评估长期感知的成功/失败对实际健康结果的影响。三项新的研究调查了实现个人目标失败的个体差异是否会影响上呼吸道感染（URI）的自我报告症状以及对流感免疫的抗体反应。基于年轻女性的试点数据，还假设月经功能障碍的发生可能与目标追求失败相互作用，以更具体地预测感冒和流感症状以及对疫苗接种的最佳反应。认为未能达到目标，并预测报告的URI症状以及抗体水平免疫后，无论是单独或与月经功能障碍。
Prior research indicates that cognitive priming manipulations that activate personal goals acutely increase or decrease natural killer cell cytotoxicity depending on whether individuals see themselves as making or failing to make progress toward their goals. Those findings in a laboratory setting revealed a psychobiological pathway whereby experiences of failure can influence health, but did not assess the impact of chronic perceived success/failure in goal pursuit on actual health outcomes. Three new studies investigated whether individual differences in perceived failure to attain personal goals influenced the self-reported symptoms of upper respiratory infections (URIs) as well as antibody response to flu immunization. Based on pilot data in young women, it also was hypothesized that the occurrence of menstrual dysfunction might interact with goal pursuit failure to more specifically predict cold and flu symptoms and optimal responses to vaccination. Perceived failure to attain goals did predict the reporting of URI symptoms as well as antibody levels post-immunization, both alone and in combination with menstrual dysfunction.