Full thickness chest wall resection for recurrent breast carcinoma involving the bony chest wall
Full thickness chest wall resection for recurrent breast carcinoma involving the bony chest wall
复制标题
全层胸壁切除术治疗累及骨性胸壁的复发性乳腺癌
作者：
J. Shah;J. Urban
孤立性复发性乳腺癌累及骨性胸壁（胸骨旁复发）是可治愈的，当没有全身扩散的证据时，发现根治性全层胸壁切除术是一种有效的治疗模式;它仍然是唯一可用的治疗胸壁复发的患者未能响应放射治疗，并在那些谁开发的并发症，由于重辐射。本报告回顾了1950年至1972年间在纪念医院接受胸壁切除术治疗的52例复发性乳腺癌患者的记录。胸壁切除和立即整形重建的技术进行了描述。接受胸壁切除术作为胸壁复发初始治疗模式的患者的大体和确定的5年生存率分别为43%和57%。另一方面，当对那些胸壁复发对放射治疗无效的患者进行胸壁切除术时，大体和确定的5年生存率下降到16%和19%。全层胸壁切除并立即整形重建作为胸壁复发的第一种治疗模式时，可提供显著的5年生存率，在复发性乳腺癌的治疗中具有明确的地位。
Solitary recurrent breast cancer involving the bony chest wall (parasternal recurrence) is curable when no evidence of systemic spread is found. Radical full thickness chest wall resection is an effective mode of treatment; it remains the only available treatment for patients whose chest wall recurrence fails to respond to radiation therapy, and in those who develop complications due to heavy irradiation. This report covers a review of the records of 52 patients treated at Memorial Hospital by chest wall resection for recurrent breast cancer between 1950 and 1972. The technique of chest wall resection and immediate plastic reconstruction is described. The gross and determinate 5‐year survival rates for patients who underwent chest wall resection as the initial mode of therapy for chest wall recurrence were 43% and 57%, respectively. On the other hand, when chest wall resection was performed on those patients whose chest wall recurrences failed to respond to radiation therapy, the gross and determinate 5‐year survival rates dropped to 16% and 19%. Full thickness chest wall resection with immediate plastic reconstruction when employed as the first mode of therapy for chest wall recurrences provides a significant 5‐year survival rate, and has a definite place in the management of recurrent breast cancer.