Assessing water-related risk factors for Buruli ulcer: A case-control study in Ghana
Assessing water-related risk factors for Buruli ulcer: A case-control study in Ghana
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DOI：
10.4269/ajtmh.2004.71.387
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发表时间：
2004-10-01
影响因子：
3.3
通讯作者：
Coleman, S
中科院分区：
文献类型：
--
作者：
Aiga, H;Amano, T;Coleman, S
为了评估与水有关的布鲁里溃疡的危险因素，在加纳对102例患者（51例病例和51例对照）进行了一项病例对照研究，这些患者的年龄组、性别和卡介苗（BCG）接种史相匹配。这里用于匹配的因子以前被认为是布鲁里溃疡（一种新兴的传染病）的因子。这是第一个研究，描绘了一组以前怀疑，水相关的危险因素，在一个病例对照研究匹配的年龄组，性别和卡介苗接种状态。多因素和双因素分析结果显示，在与水有关的主要危险因素中，只有习惯性在河流中游泳的OR值（OR = 18.00，P < 0.01）显著较高。使用河流和池塘的水作为饮用、烹饪、洗澡和洗涤目的不是显著的风险因素。我们的数据表明，游泳或与之相关的河岸活动是一个危险因素。
To assess water-related risk factors of Buruli ulcer, a case-control study of 102 patients (51 cases and 51 controls) was undertaken by matching age group, sex, and bacille Calmette-Guerin (BCG) vaccination history in Ghana. The factors used here for matching have previously been implicated as factors of Buruli ulcer, an emerging infectious disease. This is the first study to delineate a set of previously suspected, water-related risk factors, in a case-control study matching for age group, sex, and BCG vaccination status. The results of both bivariate and multivariate analyses presented a significantly high odds ratio (OR) only for swimming in rivers on a habitual basis (OR = 18.00, P < 0.01) among the major water-related risk factors. Use of water from rivers and ponds for drinking, cooking, bathing, and washing purposes were not significant risk factors. Our data suggest that swimming, or activities on riverbanks associated with it, is a risk factor.