Psychosocial Phenotyping in Women With Interstitial Cystitis/Painful Bladder Syndrome: A Case Control Study
Psychosocial Phenotyping in Women With Interstitial Cystitis/Painful Bladder Syndrome: A Case Control Study
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DOI：
10.1016/j.juro.2009.08.133
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发表时间：
2010-01-01
影响因子：
6.6
通讯作者：
Nordling, Jorgen
中科院分区：
文献类型：
--
作者：
Nickel, J. Curtis;Tripp, Dean A.;Nordling, Jorgen
目的：我们在女性间质性膀胱炎/膀胱疼痛综合征队列和年龄匹配的无诊断队列中描述和比较了心理社会表型。材料和方法：患有间质性膀胱炎/膀胱疼痛综合征的女性患者和没有该病症的对照者完成了一组心理社会表型问卷，包括人口统计学/病史表和针对一系列表现症状的有效问卷，心理社会参数和生活质量。具体措施包括间质性膀胱炎症状和问题指数、麦吉尔疼痛问卷、医疗结局研究睡眠量表、流行病学研究中心抑郁量表、状态-特质焦虑量表、疼痛灾难化量表、女性性功能指数和感知社会支持和医疗结局研究简表12生活质量的多维量表。直接比较和相关性建立组间性膀胱炎/膀胱疼痛syndrome.Results的患者的社会心理参数的差异和协会的强度：完成了207例间质性膀胱炎/膀胱疼痛syndrome患者的问卷进行了比较，117名对照组的年龄，合作伙伴的地位和教育相匹配。与对照组相比，患者报告的疼痛（总体、感觉和情感）明显更多，身体生活质量更差，睡眠功能障碍、抑郁、灾难化、焦虑、压力增加，性/社会功能问题中度增加。这些痛苦，应对和社会参数与一般疼痛的程度相关，但压力，焦虑，抑郁和灾难化进一步与IC的具体症状，并强烈降低生活质量。疼痛与身体的生活质量密切相关，而抑郁症，灾难化和压力，并在较小程度上社会支持与不良的心理quality of life.Conclusions：间质性膀胱炎/膀胱疼痛综合征患者有显着的认知和心理社会变化相比，控制。
Purpose: We characterized and compared psychosocial phenotypes in a female interstitial cystitis/painful bladder syndrome cohort and an age matched cohort without that diagnosis.Materials and Methods: Female patients with interstitial cystitis/painful bladder syndrome and controls without the condition completed a psychosocial phenotyping questionnaire battery, including a demographics/history form and validated questionnaires focused on a range of presenting symptoms, psychosocial parameters and quality of life. Specific measures included interstitial cystitis symptom and problem index, McGill Pain Questionnaire, Medical Outcomes Study Sleep Scale, Center for Epidemiological Studies Depression Scale, State-Trait Anxiety Inventory, Pain Catastrophizing Scale, Female Sexual Functioning Index and Multidimensional Scale of Perceived Social Support and Medical Outcomes Study Short Form-12 quality of life. Direct comparisons and correlations were made to establish group differences and the strength of associations for psychosocial parameters in patients with interstitial cystitis/painful bladder syndrome.Results: Questionnaires completed by 207 patients with interstitial cystitis/painful bladder syndrome were compared to those of 117 controls matched for age, partner status and education. Compared to controls patients reported significantly more pain (total, sensory and affective), worse physical quality of life, increased sleep dysfunction, depression, catastrophizing, anxiety, stress and moderately more sexual/social function problems. These suffering, coping and social parameters correlated with the degree of general pain but stress, anxiety, depression and catastrophizing further correlated with IC specific symptoms and strongly with decreased quality of life. Pain was strongly associated with physical quality of life, while depression, catastrophizing and stress, and to a lesser extent social support were associated with poor mental quality of life.Conclusions: Patients with interstitial cystitis/painful bladder syndrome have significant cognitive and psychosocial alterations compared to controls.