Childhood adiposity and fertility difficulties: the Bogalusa Heart Study
Childhood adiposity and fertility difficulties: the Bogalusa Heart Study
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DOI：
10.1111/ijpo.12168
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发表时间：
2017-12-01
影响因子：
3.8
通讯作者：
Harville, E. W.
中科院分区：
文献类型：
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作者：
Jacobs, M. B.;Bazzano, L. A.;Harville, E. W.
背景成人肥胖与不育有关；然而，儿童肥胖却很少受到关注。目的本研究旨在评估儿童肥胖对生育的影响。方法在参与心血管风险和生殖健康长期研究的女性中估计儿童肥胖与自我报告的生育困难之间的关联（n=1061）。结果9至12岁之间肥胖的参与者更有可能报告生育困难（调整后的相对风险[aRR]，1.82， 95% CI 1.17-2.82) 和尝试怀孕时无法怀孕 (aRR=1.94, 95% CI 1.22-3.08) 以及 9 岁之前肥胖的人 (aRR=1.76, 95% CI 1.04-2.97)。在童年时期超重或肥胖的人中也发现了类似的关联。肩胛下皮褶厚度高（年龄
BackgroundAdult obesity is associated with infertility; however, childhood obesity has received little consideration.ObjectivesThe present study sought to evaluate the impact of childhood adiposity on fertility.MethodsAssociations between childhood adiposity and self-reported fertility difficulties were estimated among women participating in a long-term study of cardiovascular risks and reproductive health (n=1061).ResultsParticipants with obesity between ages 9 and 12 were more likely to report fertility difficulties (adjusted relative risk [aRR], 1.82, 95% CI 1.17-2.82) and inability to become pregnant when trying (aRR=1.94, 95% CI 1.22-3.08) as were those with obesity prior to age 9 (aRR=1.76, 95% CI 1.04-2.97). Similar associations were seen among those ever overweight or obese in childhood. High subscapular skinfold thickness (age