Metabolic syndrome in Turkish children and adolescents
Metabolic syndrome in Turkish children and adolescents
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DOI：
10.1016/j.metabol.2006.03.009
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发表时间：
2006-08-01
影响因子：
9.8
通讯作者：
Ciliv, Gonenc
中科院分区：
文献类型：
--
作者：
Agirbasli, Mehmet;Cakir, Servet;Ciliv, Gonenc
本研究的目的是确定土耳其儿童和青少年代谢综合征的患病率和表型。我们将国家胆固醇教育计划成人治疗组III代谢综合征标准适用于儿童和青少年。使用国际截止点和标准，我们确定了10至17岁的土耳其儿童和青少年患有高血压，高甘油三酯（TG），低高密度脂蛋白胆固醇（HDL-C），空腹血糖100 mg/dL或更高，体重指数升高对应于超重或肥胖。我们检查了来自土耳其安卡拉的1385名10至17岁的健康学生：4.9%的受试者超重或肥胖; 29.2%的受试者具有低HDL-C和/或高TG水平; 15.7%的收缩压或舒张压高于第95个年龄，性别和身高特定百分位数。30名学生（2.2%）患有代谢综合征，具有3个或更多的风险变量。代谢综合征在超重和肥胖学生中的发生率（21%）是瘦学生的近10倍。代谢综合征的组成部分，如高血压和高TG，以及低HDL-C水平在土耳其儿童和青少年中很常见。战略应侧重于土耳其儿童这些风险变量的早期发现和治疗。(c)2006年爱思唯尔公司All rights reserved.
The aim of this study was to determine the prevalence and phenotype of metabolic syndrome in Turkish children and adolescents. We adapted the National Cholesterol Education Program Adult Treatment Panel III criteria of metabolic syndrome to children and adolescents. Using the international cutoff points and percentiles, we determined 10- to 17-year-old Turkish children and adolescents with high blood pressure, high triglyceride (TG), low high-density lipoprotein cholesterol (HDL-C), fasting glucose of 100 mg/dL or greater, and elevated body mass index corresponding to overweight or obesity. We examined 1385 apparently healthy students between the ages of 10 to 17 years from Ankara, Turkey: 4.9% of the subjects were overweight or obese; 29.2% had either low HDL-C and/or high TG levels; and 15.7% had either systolic or diastolic blood pressure above the 95th age-, sex-, and height-specific percentile. Thirty students (2.2%) had metabolic syndrome by having 3 or more risk variables. Metabolic syndrome was nearly 10 times more common among overweight and obese students (21%), compared with lean students. Components of metabolic syndrome such as high blood pressure and high TG, and low HDL-C levels were common among Turkish children and adolescents. Strategies should focus on early detection and treatment of these risk variables in Turkish children. (c) 2006 Elsevier Inc. All rights reserved.