Separation of Divalent Aromatic Anions by Capillary Zone Electrophoresis Using Multipoint Ion Association With Divalent Quaternary Ammonium Ions
Separation of Divalent Aromatic Anions by Capillary Zone Electrophoresis Using Multipoint Ion Association With Divalent Quaternary Ammonium Ions
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利用与二价季铵离子的多点离子缔合通过毛细管区带电泳分离二价芳香族阴离子
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
S. Motomizu
中科院分区：
文献类型：
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作者：
T. Takayanagi;E. Wada;S. Motomizu
使用水溶液中的离子缔合反应，然后使用聚合物涂覆的毛细管进行毛细管区带电泳，分离萘二磺酸盐 (NDS)、萘二甲酸盐 (NDC) 和邻苯二甲酸盐的位置异构体。通过使用二价季铵离子，四种NDS异构体和三种NDC异构体被完全拆分，尽管一些异构体没有被四丁基铵离子拆分。还通过使用非线性最小二乘法分析电泳迁移率的变化来确定阴离子和二价季铵阳离子之间的离子缔合常数Kass。由于静电相互作用增加，用二价阳离子获得的阴离子的 Kass 值比用四丁基铵离子获得的阴离子的 Kass 值大。离子缔合性也根据距离拟合概念和配对阳离子的疏水性概念进行了解释。通过使用更好的距离拟合配对离子也提高了离子缔合性。从所得结果来看，阳离子和阴离子分子中的电荷-电荷距离必须接近，并且二价阳离子的电荷-电荷距离比二价阴离子的电荷-电荷距离长约0.2 nm，以获得良好的离子缔合性（距离拟合概念）。
Positional isomers of naphthalenedisulfonate (NDS), naphthalenedicarboxylate (NDC) and phthalate were separated using an ion association reaction in aqueous solution followed by capillary zone electrophoresis with a polymer coated capillary. By using divalent quaternary ammonium ions, four NDS isomers and three NDC isomers were completely resolved, although some of the isomers were not resolved with tetrabutylammonium ion. Ion association constants, Kass, between the anions and the divalent quaternary ammonium cations were also determined by analyzing the change in electrophoretic mobility using a non-linear least-squares method. The Kass values of the anions obtained with the divalent cations were larger than those with tetrabutylammonium ion because of an increased electrostatic interaction. The ion associability was also explained on the basis of a distance-fitting concept and the hydrophobicity concept of the pairing cations. Ion associability was also improved by using a better distance-fitting pairing ion. From the results obtained, it was suggested that the charge–charge distance in cationic and anionic molecules must be close, and the charge–charge distance of the divalent cations was about 0.2 nm longer than that of divalent anions for good ion associability (a distance-fitting concept).