CT colonography without cathartic preparation: Feasibility study
CT colonography without cathartic preparation: Feasibility study
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DOI：
10.1148/radiology.219.3.r01jn22693
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发表时间：
2001-06-01
期刊：
影响因子：
19.7
通讯作者：
Corcoran, KE
中科院分区：
文献类型：
--
作者：
Callstrom, MR;Johnson, CD;Corcoran, KE
目得：评估方法的对比材料标记的粪便在未经准备的结肠计算机断层扫描（CT）结肠成像，并确定其敏感性polypdetection.MATERIALS和METHODS：五十六例疑似或已知息肉被分配到五组。在24或48小时内口服2 - 7剂225 mL稀释造影剂。横向CT图像评估粪便标记的有效性。所有患者均进行结肠镜检查，这是标准检查。结果：各组的平均粪便标记分数和范围如下：24小时两剂，16%和8%-21%; 24小时五剂，53%和27%-66%; 48小时四剂，38%和22%-48%; 48小时六剂，68%和54%-77%; 48小时7次给药后的总有效率为88%和75%~ 98%。两名放射科医师识别每组息肉大于或等于1 cm患者的灵敏度如下：24小时两次剂量，50%和67%; 24小时五次剂量，100%和100%; 48小时四次剂量，58%和75%; 48小时六次剂量，56%和67%;结论：口服造影剂可充分标记粪便以识别病变，需要48 h的提前期和多次剂量的造影剂。在有足够粪便标记的患者中检测息肉的灵敏度接近在准备好的结肠中检测息肉的灵敏度。
PURPOSE: To evaluate methods for contrast material labeling of stool in the unprepared colon for computed tomographic (CT) colonography and to determine their sensitivity for polyp detection.MATERIALS AND METHODS: Fifty-six patients with suspected or known polyps were assigned to five groups. Two to seven doses of 225 mL of dilute contrast material were orally administered during 24 or 48 hours. Transverse CT images were assessed for effectiveness of stool labeling. Colonoscopy was performed in all patients and was the standard. Two radiologists blinded to prior imaging and colonoscopic results assessed polyp detection.RESULTS: For each group, average stool labeling scores and ranges were as follows: 24 hour two dose, 16% and 8%-21%; 24 hour five dose, 53% and 27%-66%; 48 hour four dose, 38% and 22%-48%; 48 hour six dose, 68% and 54%-77%; and 48 hour seven dose, 88% and 75%-98%. Sensitivity for the two radiologists for the identification of patients with polyps 1 cm or larger for each group was as follows: 24 hour two dose, 50% and 67%; 24 hour five dose, 100% and 100%; 48 hour four dose; 58% and 75%; 48 hour six dose, 56% and 67%; and 48 hour seven dose, 100% and 80%.CONCLUSION: Ingestion of contrast material adequately labels stool for lesion identification; a 48-hour lead time and multiple doses of contrast material are required. Sensitivity for polyp detection in patients with adequate stool labeling approaches the sensitivity for polyp detection in prepared colons.