Distinctive Features of Female-to-Male Transsexualism and Prevalence of Gender Identity Disorder in Japan
Distinctive Features of Female-to-Male Transsexualism and Prevalence of Gender Identity Disorder in Japan
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DOI：
10.1111/j.1743-6109.2011.02252.x
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发表时间：
2011-06-01
影响因子：
3.5
通讯作者：
Saito, Tsuyoshi
中科院分区：
文献类型：
--
作者：
Baba, Tsuyoshi;Endo, Toshiaki;Saito, Tsuyoshi
变性的流行被认为是不同的社会地理背景，并在日本的流行知之甚少。多囊卵巢综合征（PCOS），这是已知的与胰岛素抵抗和代谢综合征，是常见的女性到男性（FTM）变性患者。因此，PCOS的检测是一个重要的部分，为这些individuals. Aims. The目的，本研究的目的是评估在日本的变性的患病率，以及PCOS和胰岛素抵抗的发病率之间的日本FTM transsexual patients.Methods.一百零四男性对女性（MTF）和238 FTM日本变性患者进行了研究。记录病史，包括月经周期和激素治疗史。为了排除其他疾病，如先天性肾上腺皮质增生和垂体分泌肿瘤，进行了全面的医学评估，包括经阴道或经直肠超声检查和血清激素水平和胰岛素抵抗指数的测量。主要结果测量。PCOS的诊断基于鹿特丹2003标准。MTF和FTM变性的发生率分别为每100，000人中约3.97和8.20人，使得MTF与FTM的比率约为1：2。在研究的FTM变性患者中，128名患者在最初评估之前没有服用激素（未治疗组）;其余50名患者自行服用雄激素。在未治疗组中，32.0%被诊断为PCOS，30.1%为胰岛素抵抗，31.1%表现为低脂联素血症。结论：日本变性人的性别比例与白种人不同。多囊卵巢综合征和胰岛素抵抗是常见的发现，在FTM变性患者在最初的介绍。Baba T，Endo T，Ikeda K，Shimizu A，Honnma H，Ikeda H，Masumori N，Ohmura T，Kiya T，Fujimoto T，Koizumi M，and Saito T.日本女性变男性的显著特征和性别认同障碍的患病率J Sex Med 2011;8：1686-1693.
Introduction.The prevalence of transsexualism is thought to differ among socio-geographic backgrounds, and little is known about its prevalence in Japan. Polycystic ovary syndrome (PCOS), which is known to be associated with insulin resistance and metabolic syndrome, is often seen in female-to-male (FTM) transsexual patients. Consequently, detection of PCOS is an important part of health care for these individuals.Aim.The purpose of this study was to assess the prevalence of transsexuality in Japan, as well as the incidences of PCOS and insulin resistance among Japanese FTM transsexual patients.Methods.One hundred four male-to-female (MTF) and 238 FTM Japanese transsexual patients were studied. Medical histories, including histories of menstrual cycling and hormone treatment, were taken. To exclude other diseases, such as congenital adrenal hyperplasia and hormone-secreting tumors, thorough medical assessments, including transvaginal or transrectal ultrasonography and measurement of serum hormone levels and insulin resistance indexes, were performed.Main Outcome Measures.The diagnosis of PCOS was based on the Rotterdam 2003 criteria.Results.Based on demographic statistics, the prevalences of MTF and FTM transsexuality are about 3.97 and 8.20 per 100,000 people, respectively, making the MTF-to-FTM ratio about 1:2. Of the FTM transsexual patients studied, 128 had not taken hormones before their initial assessment (untreated group); the remaining 50 self-administered androgen. Among the untreated group, 32.0% were diagnosed with PCOS, 30.1% were insulin-resistant, and 31.1% showed hypoadiponectinemia.Conclusions.The sex ratio among Japanese transsexuals is different than among Caucasians. PCOS and insulin resistance are common findings in FTM transsexual patients at initial presentation. Baba T, Endo T, Ikeda K, Shimizu A, Honnma H, Ikeda H, Masumori N, Ohmura T, Kiya T, Fujimoto T, Koizumi M, and Saito T. Distinctive features of female-to-male transsexualism and prevalence of gender identity disorder in Japan. J Sex Med 2011;8:1686-1693.