Maternal prenatal depressive symptoms and spontaneous preterm births among African-American women in Baltimore, Maryland
Maternal prenatal depressive symptoms and spontaneous preterm births among African-American women in Baltimore, Maryland
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DOI：
10.1093/aje/kwf131
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发表时间：
2002-11-01
影响因子：
5
通讯作者：
Prince, CB
中科院分区：
文献类型：
--
作者：
Orr, ST;James, SA;Prince, CB
本研究旨在探讨产妇抑郁症状与自发性早产的关系。从1991年到1993年，怀孕的非裔美国妇女被纳入马里兰州巴尔的摩的四家医院诊所，这些诊所为该市的低收入地区服务。采用流行病学研究中心抑郁量表（CES-D）评估抑郁症状。多元逻辑回归分析估计了母亲抑郁症状对自发性早产的独立贡献，控制了行为、临床和人口统计学变量。在样本中的1399名妇女中，117名（8.4%）有自然早产。自发性早产发生率在cs - d评分在前10百分位的人群中占12.7%，在得分较低的人群中占8.0%（相对风险= 1.59）。ce - d评分升高的校正优势比为1.96(95%可信区间：1.04,3.72)；因此，在这个非裔美国妇女样本中，母亲的抑郁症状与自发性早产独立相关。对孕妇的抑郁症进行有效治疗，最终可以减少自发性早产。
The purpose of this study was to examine the relation between maternal depressive symptoms and spontaneous preterm birth. From 1991 to 1993, pregnant, African-American women were prospectively enrolled at four hospital-based clinics in Baltimore, Maryland, that serve low-income areas of the city. The Center for Epidemiologic Studies Depression (CES-D) Scale was used to assess depressive symptoms. Multiple logistic regression analysis estimated the independent contribution of maternal depressive symptoms to spontaneous preterm birth, controlling for behavioral, clinical, and demographic variables. Among the 1,399 women in the sample, 117 (8.4%) had a spontaneous preterm delivery. Spontaneous preterm birth occurred among 12.7% of those with a CES-D score in the upper 10th percentile and among 8.0% of those with a lower score (relative risk = 1.59). The adjusted odds ratio for an elevated CES-D score was 1.96 (95% confidence interval: 1.04, 3.72); hence, maternal depressive symptoms in this sample of African-American women were independently associated with spontaneous preterm birth. Effective treatment of depression in pregnant women could ultimately result in a reduction of spontaneous preterm births.