The concentration of gum component in saliva before and after swallowing during prolonged gum chewing
The concentration of gum component in saliva before and after swallowing during prolonged gum chewing
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DOI：
10.1016/s0917-2394(07)70099-x
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发表时间：
2007-01-01
影响因子：
0.8
通讯作者：
Takamori, Kazunori
中科院分区：
文献类型：
--
作者：
Nakagawa, Kimiko;Watanabe, Shigeru;Takamori, Kazunori
唾液：从口香糖洗脱到唾液中的物质的浓度在吞咽前后几乎没有进行。本研究的目的是测量口腔中吞咽前（VMAX）和吞咽后（RESID）的唾液体积，还测量从口香糖咀嚼中洗脱的组分（糖）的浓度。方法：采用稀释法（Lagerlof和Dawes，1984）测定RESID。它是通过测量唾液中的钾浓度和吞咽后立即用10毫升水冲洗5秒钟后吐出的钾浓度来计算的。吞咽量计算为唾液流速除以吞咽频率，VMAX估计为RESID和吞咽唾液量之和。通过在喉部放置连接到EMG的电极来记录吞咽。口香糖中所含糖的体积为口香糖总重量的74.8%。受试者为7名男性和13名女性，他们都健康状况良好，可以测量RESID和VMAX。用分光光度计测定6名受试者的唾液糖浓度。研究结果：与未刺激唾液流速时的值相比，VMAX、吞咽频率和吞咽液体量增加。在第一次吞咽时，吐出唾液中的平均糖体积占咀嚼口香糖期间所含糖的初始重量的百分比为16.5 +/- 5.38%，第10次吞咽时为0.76 +/-0.06%。分别是未刺激唾液的3.6倍和1.8倍。
OBJECTIVES: The concentration of the substances eluted from the gum into saliva before and after swallowing has not almost carried out. The purpose of this study was to measure the volume of saliva before (VMAX) and after (RESID) swallowing in the mouth and was also to measure the concentration of the component (sugar) eluted from the gum chewing. METHODS: The RESID was measured by a dilution method (Lagerlof and Dawes, 1984). It was computed by measuring the potassium concentration in saliva and in the expectorated after a five-second rinse with 10ml of water immediately following a swallow. The volume swallowed was calculated as salivary flow rate divided by the swallowing frequency, and the VMAX was estimated as the sum of RESID and the volume of saliva swallowed. Swallows were registered by placing over the larynx an electrode which was connected to an EMG. The volume of sugar contained in the gum was 74.8% as a total weight of the gum. Subjects were seven males and 13 females who were all in good health for measuring the RESID and VMAX. For each of the six participants of them, the concentration of sugar in saliva expectorated was measured by frame photometer. RESULTS: VMAX, swallowing frequency and the volume of fluid swallowed increased as comparing with the values when the salivary flow rate was unstimulated. The mean volume of sugar in expectorated saliva as a percentage of the initial weight of sugar contained during gum chewing at the first swallowing was 16.5 +/- 5.38% and at the 10th swallowing was 0.76 +/- 0.06%. These were 3.6 times and 1.8 times of those of unstimulated saliva, respectively.