The transformative power of transformers in protein structure prediction.
The transformative power of transformers in protein structure prediction.
复制标题
蛋白质结构预测中的转换器的变革力量。
DOI:
10.1073/pnas.2303499120
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发表时间:
2023-08-08
影响因子:
11.1
通讯作者:
Bhattacharya, Debswapna
中科院分区:
文献类型:
--
作者:
Moussad, Bernard;Roche, Rahmatullah;Bhattacharya, Debswapna
Transformer neural networks have revolutionized structural biology with the ability to predict protein structures at unprecedented high accuracy. Here, we report the predictive modeling performance of the state-of-the-art protein structure prediction methods built on transformers for 69 protein targets from the recently concluded 15th Critical Assessment of Structure Prediction (CASP15) challenge. Our study shows the power of transformers in protein structure modeling and highlights future areas of improvement.
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影响因子:
64.8
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Jumper J;Evans R;Pritzel A;Green T;Figurnov M;Ronneberger O;Tunyasuvunakool K;Bates R;Žídek A;Potapenko A;Bridgland A;Meyer C;Kohl SAA;Ballard AJ;Cowie A;Romera-Paredes B;Nikolov S;Jain R;Adler J;Back T;Petersen S;Reiman D;Clancy E;Zielinski M;Steinegger M;Pacholska M;Berghammer T;Bodenstein S;Silver D;Vinyals O;Senior AW;Kavukcuoglu K;Kohli P;Hassabis D
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Hassabis D
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2.9
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通讯作者:
Grishin, Nick V.
影响因子:
2.9
作者:
Keedy, Daniel A.;Williams, Christopher J.;Richardson, Jane S.
通讯作者:
Richardson, Jane S.
影响因子:
14.9
作者:
Zemla, A
通讯作者:
Zemla, A
影响因子:
14.9
作者:
Varadi M;Anyango S;Deshpande M;Nair S;Natassia C;Yordanova G;Yuan D;Stroe O;Wood G;Laydon A;Žídek A;Green T;Tunyasuvunakool K;Petersen S;Jumper J;Clancy E;Green R;Vora A;Lutfi M;Figurnov M;Cowie A;Hobbs N;Kohli P;Kleywegt G;Birney E;Hassabis D;Velankar S
通讯作者:
Velankar S