Neighborhoods, sleep quality, and cognitive decline: Does where you live and how well you sleep matter?
Neighborhoods, sleep quality, and cognitive decline: Does where you live and how well you sleep matter?
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DOI：
10.1016/j.jalz.2017.10.007
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发表时间：
2018-04-01
影响因子：
14
通讯作者：
Hayden, Kathleen M.
中科院分区：
文献类型：
--
作者：
Hunter, Jaimie C.;Handing, Elizabeth P.;Hayden, Kathleen M.
简介：我们评估了邻里社会经济地位（NSES）和睡眠质量之间的关联认知下降的健康和退休Study.Methods：健康和退休研究参与者（n = 8090），年龄65岁以上的DNA和多个两年一次的认知观察（简称电话采访认知状态），包括。参与者被分为NSES和睡眠质量分数的四分位数。我们校正了载脂蛋白E β 4、人口统计学和心血管危险因素。随机效应模型评估认知变化随时间的推移。结果：NSES和睡眠与认知下降显着相关，它们之间有显着的相互作用（P= 0.02）。高、低NSES与高、低睡眠质量之间差异有统计学意义（P
Introduction: We evaluated the association between neighborhood socioeconomic status (NSES) and sleep quality on cognitive decline in the Health and Retirement Study.Methods: Health and Retirement Study participants (n = 8090), aged 65+ with DNA and multiple biennial cognitive observations (abbreviated Telephone Interview for Cognitive Status), were included. Participants were grouped into quartiles of NSES and sleep quality scores. We adjusted for apolipoprotein E epsilon 4, demographic, and cardiovascular risk factors. Random effects modeling evaluated cognitive change over time.Results: NSES and sleep were significantly associated with cognitive decline, and there was a significant interaction between them (P=.02). Significant differences between high/low NSES and high/low sleep quality (P