Frailty increases the risk of 30-day mortality, morbidity, and failure to rescue after elective abdominal aortic aneurysm repair independent of age and comorbidities
Frailty increases the risk of 30-day mortality, morbidity, and failure to rescue after elective abdominal aortic aneurysm repair independent of age and comorbidities
复制标题
DOI：
10.1016/j.jvs.2014.08.115
复制
发表时间：
2015-02-01
影响因子：
4.3
通讯作者：
Dodson, Thomas F.
中科院分区：
文献类型：
--
作者：
Arya, Shipra;Kim, Sung In;Dodson, Thomas F.
背景：虚弱，定义为储备减少和对应激源的抵抗力下降的生物综合征，与手术后的不良后果有关。我们评估了脆弱对择期腹主动脉瘤(AAA)修补术患者30天死亡率、发病率和抢救失败(FTR)的影响。方法：从2005年到2012年，在国家外科质量改进计划数据库中确定接受择期腹主动脉瘤修补术(EVAR)和开放式AAA修补术(OAR)的患者。使用来自加拿大健康和老龄化研究(CSHA)的修改后的脆弱指数(MFI)来评估脆弱程度。主要结果是30天的死亡率，次要结果包括30天的发病率和FTR。结果：在23207名患者中，339人死亡(1.5%；1.0%的EVAR和3.0%的OAR)
Background: Frailty, defined as a biologic syndrome of decreased reserve and resistance to stressors, has been linked to adverse outcomes after surgery. We evaluated the effect of frailty on 30-day mortality, morbidity, and failure to rescue (FTR) in patients undergoing elective abdominal aortic aneurysm (AAA) repair.Methods: Patients undergoing elective endovascular AAA repair (EVAR) or open AAA repair (OAR) were identified in the National Surgical Quality Improvement Program database for the years 2005 to 2012. Frailty was assessed using the modified frailty index (mFI) derived from the Canadian Study of Health and Aging (CSHA). The primary outcome was 30-day mortality, and secondary outcomes included 30-day morbidity and FTR. The effect of frailty on outcomes was assessed by multivariate regression analysis, adjusted for age, American Society of Anesthesiology (ASA) class, and significant comorbidities.Results: Of 23,207 patients, 339 (1.5% overall; 1.0% EVAR and 3.0% OAR) died