Use of Carbapenems, Polymyxins, and Tigecycline in United States Children's Hospitals, 2010-2014.
Use of Carbapenems, Polymyxins, and Tigecycline in United States Children's Hospitals, 2010-2014.
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DOI：
10.1093/ofid/ofx039
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发表时间：
2017
影响因子：
4.2
通讯作者：
Gerber JS
中科院分区：
文献类型：
--
作者：
Chiotos K;Ross RK;Han JH;Miller M;Gerber JS
我们对 2010 年至 2014 年间美国儿童医院使用碳青霉烯类、多粘菌素和替加环素的情况进行了分析。我们发现各医院的使用情况存在很大差异，并且随着时间的推移，总体使用情况有所下降。大多数多粘菌素和替加环素的使用发生在囊性纤维化患者中，阑尾切除术是碳青霉烯类治疗的常见适应症。
We characterized use of the carbapenems, polymyxins, and tigecycline in United States children’s hospitals between 2010 and 2014. We found substantial variability in use across hospitals and overall decreased use over time. Most polymyxin and tigecycline use occurred in cystic fibrosis patients, and appendectomy was a common indication for carbapenem therapy.