Evaluation of the Endothelial Cell Density and the Central Corneal Thickness in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma
Evaluation of the Endothelial Cell Density and the Central Corneal Thickness in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma
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DOI：
10.1155/2014/123683
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发表时间：
2014-01-01
影响因子：
1.9
通讯作者：
Mariak, Zofia
中科院分区：
文献类型：
--
作者：
Tomaszewski, Bohydar T.;Zalewska, Renata;Mariak, Zofia
目的.角膜内皮显微镜对老年性白内障合并假性剥脱综合征（PEX）合并青光眼（PEXG）和非青光眼患者中央角膜厚度（CCT）和内皮细胞密度（ECD）的评价参与者和方法。该研究包括122例患者（217只眼）。在这组患者中，我们确定了133只眼PEX综合征（65只眼青光眼，68只眼无青光眼）和84只眼无PEX综合征。通过角膜内皮显微镜测量每只眼的ECD和CCT。结果无青光眼的PEX综合征患者眼的ECD（2297 +/- 359 cell/mm（2））和PEXG患者眼的ECD（2241 +/- 363 cell/mm（2））低于对照组（2503 +/- 262 cell/mm（2））（P < 0.001）。PEXG患者的CCT（508.2 ± 32.6 μ m）比无青光眼的PEX综合征患者的CCT（529.7 ± 30.3 μ m）和对照组CCT（527.7 ± 29.4 μ m）薄（P < 0.001）。结论.这项研究表明，在患有PEX综合征的眼睛中，无论是否患有青光眼，ECD在统计学上都显著低于对照组。在PEXG患者中，CCT在统计学上显著小于PEX综合征和对照组。
Purpose. Evaluation of central corneal thickness (CCT) and endothelial cell density (ECD) in patients with senile cataract and coexisting pseudoexfoliation (PEX) syndrome with glaucoma (PEXG) and without glaucoma using specular microscopy. Participants and Methods. The study included 122 patients (217 eyes). In this group of patients we identified 133 eyes with PEX syndrome (65 with glaucoma, 68 without glaucoma) and 84 eyes without PEX syndrome. ECD and CCT were measured in each eye by specular microscopy. Results. ECD in eyes with PEX syndrome without glaucoma (2297 +/- 359 cell/mm(2)) and in eyes with PEXG (2241 +/- 363 cell/mm(2)) was lower than in the control group (2503 +/- 262 cell/mm(2)) (P < 0.001). CCT in eyes with PEXG (508.2 +/- 32.6 mu m) was thinner than in eyes with PEX syndrome without glaucoma (529.7 +/- 30.3 mu m) and control group (527.7 +/- 29.4 mu m) (P < 0.001). Conclusions. This research shows that in eyes with PEX syndrome, both with and without glaucoma, ECD was statistically significantly lower than in the control group. In patients with PEXG, CCT was statistically significantly thinner than in the PEX syndrome and control group.