USE OF INDOCYANINE GREEN AS A TEST OF LIVER FUNCTION
USE OF INDOCYANINE GREEN AS A TEST OF LIVER FUNCTION
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DOI：
10.1007/bf02232323
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发表时间：
1963-01-01
期刊：
影响因子：
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通讯作者：
HARRISON, DD
中科院分区：
文献类型：
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作者：
COOKE, AR;SKYRING, AP;HARRISON, DD
吲哚菁绿色的肝外摄取可以忽略不计，应该是一种理想的肝功能检查方法。在92名患者中使用0.1 mg/kg的剂量进行了研究，结果以10分钟时的滞留百分比表示。获得以下结果：无肝病者，0-20%滞留;肝硬化者，6-77%滞留;继发性肝癌者，25-35%滞留;活动性传染性肝炎者，22-59%滞留;恢复期肝炎9- 20%。21例肝硬化患者中只有3例的值小于20%;所有3例患者的溴磺酞保留值均正常。吲哚菁绿色保留提供了一个令人满意的和简单的肝功能测试。
Indocyanine green, which has negligible extrahepatic uptake, should be an ideal test of liver function. Its use has been investigated in 92 patients using a dose of 0.1 mg/kg and the results being expressed as percentage retention at 10 min. The following results were obtained persons without liver disease, 0-20% retention; cirrhosis of the liver, 6-77%; secondary carcinoma of the liver, 25-35%; active infectious hepatitis, 22-59%; convalescent hepatitis, 9-20%. Only 3 of 21 patients with cirrhosis had values less than 20%; all 3 had normal bromsulfalein retention values. Indocyanine green retention offers a satisfactory and simple test of liver function.