Increasing number of imported Plasmodium ovale wallikeri malaria in Shandong Province, China, 2015-2017
Increasing number of imported Plasmodium ovale wallikeri malaria in Shandong Province, China, 2015-2017
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DOI：
10.1016/j.actatropica.2019.01.015
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发表时间：
2019-03-01
期刊：
影响因子：
2.7
通讯作者：
Wei, Qingkuan
中科院分区：
文献类型：
--
作者：
Sun, Hui;Li, Jin;Wei, Qingkuan
自2012年以来，中国山东省没有报告本土疟疾病例，而输入性病例的数量和疟原虫属的遗传多样性。增加了。从2015年开始，卵形疟原虫病例数量增加，卵形疟原虫疟疾病例开始出现。2015年至2017年，共发现676例输入性疟疾病例，发现卵形疟原虫76株。分离到48株椭圆形假单胞菌和28株椭圆形假单胞菌。瓦氏卵形疟原虫疟疾病例数量逐年增加，2015年发现6例，2016年发现8例，2017年发现14例。所有病例均附有来自非洲的旅行史，来源国为赤道几内亚（n = 9）、刚果共和国（n = 4）和刚果民主共和国（n = 3）。从非洲返回山东的游客中，卵圆线虫呈上升趋势。虽然P. ovate spp.感染很少进展到严重程度，怀疑该种属产生具有复发潜力的催眠虫。导致复发的能力是对公共卫生的威胁，应该引起关注。
Since 2012, no indigenous malaria case have been reported in Shandong Province, China, whereas the number of imported cases and the genetic diversity of Plasmodium spp. have increased. Beginning in 2015, the number of Plasmodium ovate cases were increased and the P. ovate wallikeri malaria case began to arise. From 2015 to 2017, a total of 676 imported malaria cases were detected and 76 P. ovate spp. isolates were identified, of which 48 were P. ovals curtisi and 28 P. ovals wallikeri. The number of P. ovate wallikeri malaria cases increased yearly, six were identified in 2015, eight were identified in 2016, and 14 were identified in 2017. All cases with an attached travel history from Africa, with represented source countries of Equatorial Guinea (n = 9), Republic of the Congo (n = 4), and Democratic Republic of the Congo (n = 3). P. ovate wallikeri is increasing among travelers returning to Shandong Province from Africa. Although the P. ovate spp. infection rarely progressed to severity, this species is suspected to generate hypnozoites which have the potential to relapse. The ability to cause relapse is the threat to public health and should be concerned.