Techniques for analysis of biological aging.
Techniques for analysis of biological aging.
复制标题
生物衰老分析技术。
DOI：
10.1007/978-1-59745-361-5_1
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Tollefsbol,TrygveO
中科院分区：
文献类型：
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作者：
Tollefsbol,TrygveO
衰老过程包括分子、细胞和有机体水平的变化，可以通过多种方法进行分析。几十年来，研究生物衰老的一种流行模式是分析体外培养的显示细胞衰老的细胞。目前的兴趣还集中在衰老模型，包括生物体衰老，例如酵母和果蝇的衰老。过去十年中，应用于生物衰老的技术数量呈指数级增长。尽管生物衰老的方法差异很大，但它们通常可以分为基本技术、干预方法和用于分析衰老细胞中许多分子和细胞变化的方案。因此，本书将主题分为这三类。
The aging process encompasses changes at the molecular, cellular, and organismal levels that can be analyzed by a variety of methods. For several decades, a popular mode of studying biological aging has been the analysis of cells cultured in vitro that display cellular senescence. Current interest is also focused on models of senescence that include organismal aging such as aging of yeast andDrosophila. The number of techniques applied to biological aging has increased exponentially over the past decade. Although approaches to biological aging vary greatly, they can be generally grouped into basic techniques, intervention methods, and protocols for analyzing the many molecular and cellular changes seen in aging cells. Hence, this volume organizes the topics into these three categories.