SILICONE-RUBBER SUBSTRATA - NEW WRINKLE IN THE STUDY OF CELL LOCOMOTION
SILICONE-RUBBER SUBSTRATA - NEW WRINKLE IN THE STUDY OF CELL LOCOMOTION
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DOI：
10.1126/science.6987736
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发表时间：
1980-01-01
期刊：
影响因子：
56.9
通讯作者：
STOPAK, D
中科院分区：
文献类型：
--
作者：
HARRIS, AK;WILD, P;STOPAK, D
当组织细胞在非常薄的交联硅油片上培养时，细胞施加的牵引力作为该基质的弹性变形和扭曲而可见。在移植物周围，这种模式非常类似于在血浆凝块中长期观察到的“中心效应”，传统上归因于脱水收缩。
When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum. Around explants this pattern of wrinkling closely resembles the "center effects" long observed in plasma clots and traditionally attributed to dehydration shrinkage.