Primary bacterial infection of the myocardium
Primary bacterial infection of the myocardium
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DOI：
10.2741/1021
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发表时间：
2003-05-01
期刊：
影响因子：
--
通讯作者：
Shuter, J
中科院分区：
文献类型：
--
作者：
Wasi, F;Shuter, J
心肌组织原发细菌感染而不伴有心内膜炎的情况很少发生。它通常出现在压倒性菌血症的情况下。最常见的细菌性心肌炎的原因是金黄色葡萄球菌，虽然感染范围广泛的细菌病原体已被描述。病理上，该病的特点是心肌多灶性分布，伴有微小脓肿，最常累及左心室。并发症包括心功能障碍、心律失常和继发化脓性心包炎的心肌破裂。由于几乎所有关于原发性细菌性心肌炎的信息都来自前抗生素时代进行的尸检研究，因此对这种临床实体的现代诊断和管理方法知之甚少。
Primary bacterial infection of myocardial tissue without associated endocarditis occurs only rarely. It is generally seen in the setting of overwhelming bacteremia. The most common bacterial cause of myocarditis is Staphylococcus aureus, although infections with a broad range of bacterial pathogens have been described. Pathologically, the disease process is characterized by multifocal studding of the myocardium with tiny abscesses, and the left ventricle is most commonly involved. Complications include cardiac dysfunction, rhythm disturbances, and myocardial rupture with secondary purulent pericarditis. Since virtually all information regarding primary bacterial myocarditis originates from autopsy studies conducted in the pre-antibiotic era, little is known about the modern approach to diagnosis and management of this clinical entity.