The first conversion of primary alkyl halides to nitroalkanes under aqueous medium
The first conversion of primary alkyl halides to nitroalkanes under aqueous medium
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DOI：
10.1021/jo049048b
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发表时间：
2004-10-01
影响因子：
3.6
通讯作者：
Giarlo, G
中科院分区：
文献类型：
--
作者：
Ballini, R;Barboni, L;Giarlo, G
在水介质中，相应的光环衍生物与亚硝酸盐银反应可得到伯硝基烷烃和-，-二硝基烷烃。该方法对烷基溴化物和烷基碘化物都很有效，即使在存在其他官能团的情况下，也能取得令人满意的好收率，最大限度地减少了不需要的烷基亚硝酸盐的形成。
Primary nitroalkanes and alpha,omega-dinitroalkanes can be easily obtained in aqueous medium by reaction of the corresponding halo derivatives with silver nitrite. The procedure works well with both alkyl bomide and alkyl iodide and proceeds in satisfactory to good yields even in the presence of other functionalities, minimizing the formation of the undesired alkyl nitrites.