Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation

Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation
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DOI:
10.1002/jmv.26368
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发表时间:
2020-08-17
影响因子:
12.7
通讯作者:
Sivan, Manoj
Sivan, Manoj
中科院分区:
医学3区
文献类型:
--
作者:
Halpin, Stephen J.;McIvor, Claire;Sivan, Manoj

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背景目前关于出院后COVID-19后症状的性质和患病率的信息非常有限。方法一个有目的的样本100名幸存者从一所大型大学医院出院后4至8周进行了评估,由一个多学科的康复专业人员使用专门的电话筛选工具,旨在捕捉症状和对日常生活的影响。EQ-5D-5L电话版也已完成。结果研究对象为出院后29 ~ 71天(平均48天)。32名参与者需要在重症监护室(ICU组)接受治疗,68名参与者在医院病房接受治疗,无需ICU护理(病房组)。ICU组72%和病房组60.3%的患者报告的最常见症状为新发疾病相关性疲乏。其次是呼吸困难(ICU组65.6%,病房组42.6%)和心理困扰(ICU组46.9%,病房组23.5%)。ICU组EQ 5D下降率为68.8%,病房组为45.6%。结论:这是第一项来自英国的研究报告出院后症状。我们建议规划康复服务,以适当管理这些症状,并最大限度地恢复COVID-19幸存者的功能。
Background There is currently very limited information on the nature and prevalence of post-COVID-19 symptoms after hospital discharge. Methods A purposive sample of 100 survivors discharged from a large University hospital were assessed 4 to 8 weeks after discharge by a multidisciplinary team of rehabilitation professionals using a specialist telephone screening tool designed to capture symptoms and impact on daily life. EQ-5D-5L telephone version was also completed. Results Participants were between 29 and 71 days (mean 48 days) postdischarge from hospital. Thirty-two participants required treatment in intensive care unit (ICU group) and 68 were managed in hospital wards without needing ICU care (ward group). New illness-related fatigue was the most common reported symptom by 72% participants in ICU group and 60.3% in ward group. The next most common symptoms were breathlessness (65.6% in ICU group and 42.6% in ward group) and psychological distress (46.9% in ICU group and 23.5% in ward group). There was a clinically significant drop in EQ5D in 68.8% in ICU group and in 45.6% in ward group. Conclusions This is the first study from the United Kingdom reporting on postdischarge symptoms. We recommend planning rehabilitation services to manage these symptoms appropriately and maximize the functional return of COVID-19 survivors.