Cobalt-catalyzed Heck-type reaction of alkyl halides with styrenes
Cobalt-catalyzed Heck-type reaction of alkyl halides with styrenes
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DOI：
10.1021/ja026296l
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发表时间：
2002-06-12
影响因子：
15
通讯作者：
Oshima, K
中科院分区：
文献类型：
--
作者：
Ikeda, Y;Nakamura, T;Oshima, K
钴配合物CoCl 2 [1，6-双（二苯基膦基）己烷]在Me 3SiCH 2 MgCl存在下在乙醚中催化苯乙烯的烷基化反应生成β-烷基苯乙烯。包括烷基氯的各种烷基卤化物可用作烷基源。一个自由基机制强烈建议为这个烷基化反应。
A cobalt complex, CoCl2[1,6-bis(diphenylphosphino)hexane], catalyzes an alkylation reaction of styrenes in the presence of Me3SiCH2MgCl in ether to yield β-alkylstyrenes. A variety of alkyl halides including alkyl chlorides can be employed as an alkyl source. A radical mechanism is strongly suggested for this alkylation reaction.