Visceral and subcutaneous adiposity measurements in adults: Influence of measurement site
Visceral and subcutaneous adiposity measurements in adults: Influence of measurement site
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DOI：
10.1038/oby.2007.172
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发表时间：
2007-06-01
期刊：
影响因子：
6.9
通讯作者：
Carr, Andrew
中科院分区：
文献类型：
--
作者：
Ellis, Kenneth J.;Grund, Birgit;Carr, Andrew
目的：腹部过度肥胖是心血管疾病的已知危险因素。计算机断层扫描可用于检查腹部肥胖的内脏 (VAT) 和皮下 (SAT) 成分，但是否需要单层还是多层协议尚未解决。 研究方法和程序：对 24 名成人的腰椎区域进行了 9 次计算机断层扫描。九个切片是在三个椎间位置（L2-L3、L3-L4 和 L4-L5）以及这些位置上方和下方 7 mm 处获得的。使用方差分析和平均值之间成对差异的置信区间检查 SAT、VAT、总脂肪组织和 VAT/SAT 比率的位点内和位点间差异。结果：椎间 SAT 值从 L2-L3 的 103.1 +/- 50.9（标准差） cm(2) 增加到 L4-L5 的 153.3 +/- 68.8 cm(2)，而相应的 VAT 值从164.3 +/- 125.4 至 126.0 +/- 82.7 厘米(2)。 VAT/SAT 比率并非恒定，从 1.8 +/- 1.4 降至 0.9 +/- 0.7。重复测量方差分析表明站点间和站点内存在显着差异 (p
Objective: Excess abdominal adiposity is a known risk factor for cardiovascular diseases. Computed tomography can be used to examine the visceral (VAT) and subcutaneous (SAT) components of abdominal adiposity, but it is unresolved whether single-slice or multi-slice protocols are needed.Research Method and Procedures: Nine computed tomography scans were obtained in the lumbar spine region of 24 adults. The nine slices were obtained at three intervertebral positions (L2-L3, L3-L4, and L4-L5) and at 7 mm above and below these locations. Intra-site and inter-site differences in SAT, VAT, total adipose tissue, and the VAT/SAT ratio were examined using ANOVA and confidence intervals for pairwise differences between means.Results: Intervertebral SAT values increased from 103.1 +/- 50.9 (standard deviation) cm(2) at L2-L3 to 153.3 +/- 68.8 cm(2) at L4-L5, whereas the corresponding VAT values decreased from 164.3 +/- 125.4 to 126.0 +/- 82.7 cm(2). The VAT/SAT ratio was not constant, decreasing from 1.8 +/- 1.4 to 0.9 +/- 0.7. Repeated-measures ANOVA indicated significant inter- and intra-site differences (p