The Early Phase of Cryogenic Lesions: An Experimental Model of Seizures Updated
The Early Phase of Cryogenic Lesions: An Experimental Model of Seizures Updated
复制标题
低温病变的早期阶段：更新癫痫发作的实验模型
作者：
H. Loiseau;N. Avéret;E. Arrigoni;F. Cohadon
总结：:对64只家兔冷冻损伤后23 h内的癫痫活动和脑灰质水肿进行了相关性研究。指数的发展，使定量评估癫痫活动。这些指标表明，冷冻癫痫的早期阶段是一个非常迅速的现象，在第一个4小时内的损害后。癫痫活动先于脑水肿，在个别动物中，癫痫活动总量与水肿总量之间存在显著正相关。癫痫活动和脑水肿之间的关系在病理生理机制水平上最有可能相互关联，并且可以假设几种机制。
Summary: : Following cryogenic lesions in 64 rabbits, epileptic activity and gray matter edema were correlatively investigated during the initial phase (23 h). Indexes were developed to allow a quantitative assessment of epileptic activity. The indexes demonstrated that the early phase of cryogenic epilepsy is a very rapid phenomenon during the first 4 h postlesion. Epileptic activity precedes brain edema, and in individual animals, there is a significant positive correlation between the total amount of epileptic activity and the total amount of edema. The relationship between epileptic activity and brain edema are most likely interrelated at the level of pathophysiological mechanisms and several mechanisms can be postulated.
局灶性癫痫发作的代谢和病理后果。
DOI：
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发表时间：
1983
期刊：
Research publications - Association for Research in Nervous and Mental Disease
影响因子：
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作者：
Collins,RC;Olney,JW;Lothman,EW
通讯作者：
Lothman,EW