Getah virus infection of Indian horses
Getah virus infection of Indian horses
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DOI：
10.1023/a:1005079229232
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发表时间：
1998-08-01
影响因子：
1.7
通讯作者：
Timoney, PJ
中科院分区：
文献类型：
--
作者：
Brown, CM;Timoney, PJ
1990年在印度的一个纯种马农场爆发了一场疾病，其特征是抑郁、厌食、发烧、肢体水肿和淋巴细胞减少。农场88匹马中有26匹受到影响，主要是成年马。感染马的症状持续7-10天，疫情持续21天。使用配对血清样本（急性期和恢复期）对26匹受影响马中的7匹进行了Getah病毒暴露试验。7匹马中有4匹血清转化为Getah病毒，另外3匹显示滴度升高4倍或更高。临床和实验室结果与日本马自然和实验感染中描述的结果相似，但不完全相同。这是第一次描述的疾病引起的盖塔病毒感染的马在日本以外。此外，还对来自印度3个地区的152匹马的血清样品进行了评价，以确定是否存在盖塔病毒抗体。发现血清阳性率为17%，表明印度马在其他地方暴露于病毒。
An outbreak of disease, characterized by depression, anorexia, fever, limb oedema and lymphocytopenia, occurred on a farm for thoroughbreds in India in 1990. Twenty-six of the 88 horses on the farm were affected, predominantly adults. Signs were present in affected horses for 7-10 days, and the outbreak lasted 21 days. Seven of the 26 affected horses were tested for exposure to Getah virus using paired serum samples, acute and convalescent. Four of the 7 horses seroconverted to Getah virus, and the other three showed a 4-fold or greater rise in titre. The clinical and laboratory findings were similar, but not indentical, to those described in natural and experimental infections in Japanese horses. This is the first description of disease caused by Getah virus infection in horses outside Japan. In addition serum samples from 152 horses from 3 regions of India were evaluated for the presence of antibodies to Getah virus. The seroprevalence was found to be 17%, indicating exposure to the virus elsewhere in Indian horses.