BioNØT: a searchable database of biomedical negated sentences.
BioNØT: a searchable database of biomedical negated sentences.
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DOI:
10.1186/1471-2105-12-420
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发表时间:
2011-10-27
影响因子:
3
通讯作者:
Kohane I
中科院分区:
文献类型:
--
作者:
Agarwal S;Yu H;Kohane I
Negated biomedical events are often ignored by text-mining applications; however, such events carry scientific significance. We report on the development of BioN∅T, a database of negated sentences that can be used to extract such negated events. Currently BioN∅T incorporates ≈32 million negated sentences, extracted from over 336 million biomedical sentences from three resources: ≈2 million full-text biomedical articles in Elsevier and the PubMed Central, as well as ≈20 million abstracts in PubMed. We evaluated BioN∅T on three important genetic disorders: autism, Alzheimer's disease and Parkinson's disease, and found that BioN∅T is able to capture negated events that may be ignored by experts. The BioN∅T database can be a useful resource for biomedical researchers. BioN∅T is freely available at http://bionot.askhermes.org/. In future work, we will develop semantic web related technologies to enrich BioN∅T.
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