Development of fetal movement - Fetal heart rate coupling from 20 weeks through term
Development of fetal movement - Fetal heart rate coupling from 20 weeks through term
复制标题
DOI：
10.1016/0378-3782(95)01704-6
复制
发表时间：
1996-02-23
影响因子：
2.5
通讯作者：
Johnson, TRB
中科院分区：
文献类型：
--
作者：
Dipietro, JA;Hodgson, DM;Johnson, TRB
本研究记录了从孕20周到足月的健康胎儿对胎动（FM）的反应性胎心率（FHR）变化的发展。31例胎儿分别于20、24、28、32、36、38-39周接受50 min多普勒监测，连续数字化FHR和FM。耦合指数计算为在运动开始的-5或+15 s内与FHR增加5次/min或更多相关的FM的百分比。还计算了FM开始和FHR变化之间的潜伏期，以及所有运动的幅度和持续时间。随着孕龄的增加，FM与FHR的结合越来越紧密，耦合度增加，FM与FHR变化的潜伏期缩短。母亲年龄、血压和胎儿性别对FM-FHR偶联无影响，但生活压力大、心率快的孕妇胎儿FM-FHR偶联降低，提示FM-FHR偶联的发生反映了妊娠期中枢神经系统的发育，其发育可能受母体因素的影响。
This study documents the development of fetal heart rate (FHR) change in response to fetal movement (FM) in healthy fetuses from 20 weeks' gestational age through term. Thirty-one fetuses received 50 min of Doppler-based monitoring at 20, 24, 28, 32, 36 and 38-39 weeks, FHR and FM were continuously digitized. A coupling index was computed as the percentage of FMs associated with increases in FHR of 5 beats/min or more within -5 or +15 s of movement onset, The latency between FM onset and FHR change was also computed, as were the amplitude and duration of all movements. FM and FHR became more integrated with advancing gestation, Coupling increased and the latency between FM and FHR changes decreased. Maternal age, blood pressure and fetal sex did not affect FM-FHR coupling, but fetuses of women who reported greater stress in their daily lives and had faster heart rates displayed reduced coupling, These data suggest that the development of FM-FHR coupling reflects the development of the central nervous system during gestation, and that development may be affected by maternal factors.