The intravoxel incoherent motion MRI of lateral pterygoid muscle: a quantitative analysis in patients with temporomandibular joint disorders
The intravoxel incoherent motion MRI of lateral pterygoid muscle: a quantitative analysis in patients with temporomandibular joint disorders
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DOI：
10.1259/dmfr.20160424
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发表时间：
2017-01-01
影响因子：
3.3
通讯作者：
Kurabayashi, Tohru
中科院分区：
文献类型：
--
作者：
Ngamsom, Supak;Nakamura, Shin;Kurabayashi, Tohru
目的：目的：应用体素内非相干运动（IVIM）成像技术定量评价颞下颌关节紊乱病（TMD）患者翼外肌（LPM）的弥散和灌注状态，并与常规MRI所见进行对照。为了评估IVIM参数，通过基于自旋回波的单次激发回波平面成像获得弥散加权成像。在b值为0-500 smm（-2）的翼外肌上级腹（SLP）和翼外肌下腹（ILP）的所有弥散加权图像上创建感兴趣区域。然后，使用双指数拟合计算IVIM参数、扩散（D）和灌注（f）。结果：对于SLP，关节盘前移位未复位的TMJ的f参数显著高于正常TMJ（p=0.015）。有关节积液的颞下颌关节也显著高于无关节积液的颞下颌关节（p=0.016）。另一方面，对于SLP和ILP，与无骨关节炎的TMJ相比，D参数显著增加（分别为p=0.015和p=0.022）。
Objectives: To quantitatively evaluate diffusion and perfusion status of lateral pterygoid muscle (LPM) in patients with temporomandibular joint disorder (TMD) by intravoxel incoherent motion (IVIM) imaging and to correlate with findings on temporomandibular joints (TMJs) by conventional MRI.Methods: 42 patients with TMD underwent MRI. To assess IVIM parameters, diffusion-weighted imaging was obtained by spin-echo-based single-shot echoplanar imaging. Regions of interest were created on all diffusion-weighted images of the superior belly of the lateral pterygoid (SLP) and inferior belly of the lateral pterygoid (ILP) at b-values 0-500 smm(-2). Then, IVIM parameters, diffusion (D) and perfusion (f) were calculated using biexponential fittings. The correlation of these values with conventional MRI findings on TMJs was investigated.Results: For SLP, the f parameter in TMJs with anterior disc displacement without reduction was significantly higher than that in normal ones (p=0.015). It was also significantly higher in TMJs with joint effusion than in those without (p=0.016). On the other hand, for both SLP and ILP, the D parameter significantly increased in TMJs with osteoarthritis compared with those without (p=0.015 and p=0.022, respectively).Conclusions: Pathological changes of LPM in patients with TMD may be quantitatively evaluated by IVIM parameters.