Dysembryoplastic neuroepithelial tumors: MR and CT evaluation.
Dysembryoplastic neuroepithelial tumors: MR and CT evaluation.
复制标题
胚胎发育不良性神经上皮肿瘤：MR 和 CT 评估。
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
H. Schild
中科院分区：
文献类型：
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作者：
B. Ostertun;H. Wolf;M. Campos;C. Matus;L. Solymosi;C. Elger;J. Schramm;H. Schild
PURPOSE
To evaluate dysembryoplastic neuroepithelial tumors (DNTs) on MR and CT studies and to compare DNT with other frequently encountered epileptogenic glioneuronal lesions.
METHODS
We analyzed the MR images and CT scans of 16 patients who had complex partial epilepsy and DNT with respect to tumor location, size, CT density, MR signal intensity, mass effect, contrast enhancement, and heterogeneity, and compared these features with CT and MR findings in 51 cases of ganglioglioma and 33 cases of glioneuronal malformation.
RESULTS
DNTs were located in the temporal lobe in 14 patients and in the frontal lobe in 2 patients. The cortex was involved in all cases and the subcortical white matter in 10 cases. Fifty percent of the tumors had poorly defined contours. On MR images, 14 DNTs had multiple cysts and 2 had single cysts. Contrast enhancement was observed in 6 DNTs, and mass effect was present in 9. CT scans disclosed moderately hypodense lesions in 7 patients and markedly hypodense cystic lesions in 6 patients. Two DNTs were calcified. Tumor hemorrhage with perifocal edema was observed in 1 case. Contrary to previous reports, slow but definite tumor growth was present during a 13-year period in 2 of 6 patients in whom serial CT or MR studies were obtained.
CONCLUSION
A multicystic appearance on MR images is a characteristic feature of DNT and corresponds to its myxoid matrix and multinodular architecture. This feature is rare in gangliogliomas and glioneuronal malformations, and, as such, may help differentiate DNTs from these disorders.
