The value of traditional upper endoscopy as a diagnostic test for Barrett's esophagus
The value of traditional upper endoscopy as a diagnostic test for Barrett's esophagus
复制标题
DOI：
10.1016/j.gie.2008.02.064
复制
发表时间：
2008-11-01
影响因子：
7.7
通讯作者：
Eisen, Glenn M.
中科院分区：
文献类型：
--
作者：
Wang, Amy;Mattek, Nora C.;Eisen, Glenn M.
背景：诊断Barrett‘s食道(BE)的标准检查是传统的上消化道内窥镜检查。目的：确定BE的总体准确性，以及影响传统上消化道内窥镜诊断BE准确性的因素。背景：13个学术、社区和退伍军人事务网站。设计：一项回顾性数据回顾。患者：接受上消化道内窥镜检查的患者，发现“疑似Barrett‘s食道”和食道活检。检查病理报告以确定肠化生的病例。主要结果测量：病理证实的BE在疑似病例中的百分比。结果：总共检查了2511例手术；活检证实的BE的频率为48.4%。多因素Logistic回归分析显示，以下因素与活检确诊BE独立相关：被测量的长节段：3 cm(优势比[OR]4.61[95%CI，3.73-5.69])，男性(OR 1.82[95%CI，1.49-2.22])，年龄增长(年龄区间70-79岁，与年龄相比OR 2.33
Background: The standard test for diagnosing Barrett's esophagus (BE) is a conventional upper endoscopy. However, studies have shown that confirmation of BE by endoscopy with histologic intestinal metaplasia can be difficult.Objective: To determine the overall accuracy, as well as factors that influence the accuracy of a conventional upper endoscopy in diagnosing BE.Setting: Thirteen academic, community, and Veterans Affairs sites.Design: A retrospective data review.Patients: Patients who underwent an upper endoscopy with a finding of "suspected Barrett's esophagus" and esophageal biopsies. Pathology reports were examined to identify cases with intestinal metaplasia.Main Outcome Measurements: Percentage Of pathology-confirmed BE among suspected cases.Results: A total of 2511 procedures were examined; the frequency of biopsy-confirmed BE was 48.4%. Multivariate logistic regression identified the following factors to be independently associated with biopsy-confirmed BE: long-segment BE that measured :3 cm (odds ratio [OR] 4.61 [95% CI, 3.73-5.69]), male sex (OR 1.82 [95% CI, 1.49-2.22]), increasing age (age interval 70-79 years with OR 2.33 compared with age