Impact of human immunodeficiency virus on neurocognition and risky behaviors in young adults
Impact of human immunodeficiency virus on neurocognition and risky behaviors in young adults
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DOI：
10.1007/s13365-014-0264-4
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发表时间：
2014-10-01
影响因子：
3.2
通讯作者：
Ances, Beau M.
中科院分区：
文献类型：
--
作者：
Baker, Laurie M.;Paul, Robert H.;Ances, Beau M.
以前的研究已经确定了成人中人类免疫缺陷病毒（HIV）引起的认知障碍。然而，很少有研究探讨艾滋病毒对年轻人（18-24岁）认知的影响。然而，这一群体是新感染艾滋病毒的最大人群之一。青年期也是一个重要的发育窗口，因为大脑尚未完全成熟，个体容易从事危险行为。本研究的目的是探讨艾滋病毒对神经认知和危险行为的影响。我们假设HIV阳性的年轻人（n=23）与血清阴性的对照组（n=21）相比，会表现出更大的认知障碍和危险行为。此外，我们预测，自我报告的危险行为评估的风险评估电池（RAB）将与认知性能协变。结果显示，执行功能较差的艾滋病毒阳性的年轻人相比，血清阴性（艾滋病毒-）的控制。HIV阳性的年轻人在RAB上表现出显著更高的风险评分（p
Previous studies have identified cognitive impairments due to human immunodeficiency virus (HIV) in adults. However, few studies have examined the impact of HIV on cognition in young adults (18-24 years old). Yet, this group is one of the largest populations of individuals with new HIV infection. Young adulthood is also an important developmental window because the brain has not fully matured and individuals are prone to engage in risky behavior. The purpose of the present study was to examine the impact of HIV on neurocognition and risky behaviors. We hypothesized that HIV+ young adults (n=23) would exhibit greater cognitive impairment and risky behaviors compared to seronegative controls (n=21). In addition, we predicted that self-reported risky behavior as assessed by the Risk Assessment Battery (RAB) would covary with cognitive performances. Results revealed poorer executive function in HIV+ young adults compared to seronegative (HIV-) controls. HIV+ young adults exhibited significantly greater risk scores on the RAB (p