APACHE-II score correlation with mortality and length of stay in an intensive care unit.
APACHE-II score correlation with mortality and length of stay in an intensive care unit.
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发表时间：
2011
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通讯作者：
Saad Ahmed Naved;S. Siddiqui;F. Khan
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作者：
Saad Ahmed Naved;S. Siddiqui;F. Khan
目的探讨APACHE-II评分系统与ICU病死率及住院时间的相关性。研究设计队列研究。研究地点和持续时间：2005年5月至2006年5月，卡拉奇的阿加汗大学医院重症监护室（ICU）。方法所有入住ICU的成年患者均纳入研究。在ICU入院的第2天和第7天计算APACHE-II评分。将首次APACHE-II评分（第2天）后从ICU存活出院或死亡的患者记录为主要结局指标。采用第二次APACHE-II评分（第7天）预测ICU住院时间。皮尔森相关系数（r）被确定为具有p < 0.05的显著性。结果在最低评分3-10分的30例患者中，27例（90%）出院，仅3例（10%）死亡。在APACHE-II评分为高分类31-40的39例患者中，观察到33例（84.6%）死亡。这表明，在APACHE-II评分较高的情况下，死亡的可能性可能更大（p=0.001）。APACHE-II评分与ICU住院时间呈负相关（r =-0.084，p < 0.183），但无统计学意义。结论APACHE-II评分系统可用于根据疾病严重程度对患者进行分类。高分与住院时间以及死亡率之间呈负相关。
OBJECTIVE To correlate the APACHE-II score system with mortality and length of stay in ICU. STUDY DESIGN Cohort study. PLACE AND DURATION OF STUDY The Intensive Care Unit (ICU) of the Aga Khan University Hospital, Karachi, from May 2005 to May 2006. METHODOLOGY All adult patients who were admitted in the ICU were included. APACHE-II score was calculated at the second and seventh days of admission in the ICU. Patients who were discharged alive from the ICU or died after first APACHE-II Score (at 2nd day) were noted as the primary outcome measurement. Second APACHE-II score (at 7th day) was used to predict the length of stay in the ICU. Pearson's correlation coefficient (r) was determined with significance at p < 0.05. RESULTS In the lowest score category 3-10, 27 out of 30 patients (90%) were discharged and only 3 (10%) died. Out of those 39 patients whose APACHE-II score was found in high category 31-40, 33 (84.6%) deaths were observed. This revealed that there might be more chances of death in case of high APACHE-II score (p=0.001). Insignificant but an inverse correlation (r = -0.084, p < 0.183) was observed between APACHE-II score and length of ICU stay. CONCLUSION The APACHE-II scoring system was found useful for classifying patients according to their disease severity. There was an inverse relationship between the high score and the length of stay as well higher chances of mortality.