Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain
Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain
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DOI：
10.1016/s0968-0004(01)01861-8
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发表时间：
2001-07-01
影响因子：
13.8
通讯作者：
D'Esposito, M
中科院分区：
文献类型：
--
作者：
Filippini, F;Rossi, V;D'Esposito, M
这篇文章描述了一个新的SNARE结构域的发现，它可能参与膜融合的调节，这个结构域是由一个新的VAMP家族共享的，称为长VAMP或longins。这个家族的成员在真核生物中比经典的VAMP更保守，可能是因为它们潜在的基本SNARE功能。
This article describes the discovery of a novel SNARE domain that might be involved in the regulation of membrane fusion, This domain is shared by a novel family of VAMPs called long VAMPs or longins. Members of this family are more conserved among eukaryotes than are classical VAMPs, possibly because of their underlying basic SNARE function.