Interobserver reliability of visual interpretation of electroencephalograms in children with newly diagnosed seizures
Interobserver reliability of visual interpretation of electroencephalograms in children with newly diagnosed seizures
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DOI：
10.1017/s0012162206000806
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发表时间：
2006-05-01
影响因子：
3.8
通讯作者：
van Donselaar, CA
中科院分区：
文献类型：
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作者：
Stroink, H;Schimsheimer, RJ;van Donselaar, CA
脑电(EEG)视觉解释的可靠性对于评估这一诊断工具的价值非常重要。我们前瞻性地获得了93例儿童(男56例，女37例)部分睡眠剥夺后的50个标准脑电和61个脑电图，这些儿童平均年龄6岁10个月(SE5mo；范围4mo-15y7mo)，并伴有一次或多次新诊断的无缘性惊厥。两位临床神经生理学家独立地对每个脑电的背景模式和癫痫样放电或局灶性非癫痫样异常的存在进行了分类。对于脑电的正常或异常(kappa 0.66)，对于癫痫样放电的存在几乎是完美的(kappa 0.83)，对于异常背景模式的出现(kappa 0.73)，以及对于局灶性非癫痫样放电的存在(kappa 0.54)，这一共识是实质性的。总而言之，对于癫痫样异常的存在，儿童脑电视觉解释的可靠性几乎是完美的，对于其他异常的存在，则是中度到实质性的。
The reliability of visual interpretation of electroencephalograms (EEG) is of great importance in assessing the value of this diagnostic tool. We prospectively obtained 50 standard EEGs and 61 EEGs after partial sleep deprivation from 93 children (56 males, 37 females) with a mean age of 6 years 10 months (SE 5mo; range 4mo-15y 7mo) with one or more newly diagnosed, unprovoked seizures. Two clinical neurophysiologists independently classified the background pattern and the presence of epileptiform discharges or focal non-epileptiform abnormalities of each EEG. The agreement was substantial for the interpretation of the EEG as normal or abnormal (kappa 0.66), almost perfect for the presence of epileptiform discharges (kappa 0.83), substantial for the occurrence of an abnormal background pattern (kappa 0.73), and moderate for the presence of focal non-epileptiform discharges (kappa 0.54). In conclusion, the reliability of the visual interpretation of EEGs in children is almost perfect as regards the presence of epileptiform, abnormalities, and moderate to substantial for the presence of other abnormalities.