Thermo-Responsive Polymer Brushes as Intelligent Biointerfaces: Preparation via ATRP and Characterization
Thermo-Responsive Polymer Brushes as Intelligent Biointerfaces: Preparation via ATRP and Characterization
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DOI：
10.1002/mabi.201000312
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发表时间：
2011-03-10
影响因子：
4.6
通讯作者：
Okano, Teruo
中科院分区：
文献类型：
--
作者：
Nagase, Kenichi;Watanabe, Minami;Okano, Teruo
通过表面引发ATRP制备了具有不同接枝密度和链长的PIPAAm刷接枝玻璃基底。通过ATR/FT-IR光谱、XPS、AFM和接触角测量，表征了表面的温度依赖性物理化学性质。ATRP条件影响接枝的PIPAAm的量和基底的表面润湿性和粗糙度。随着PIPAAm刷密度的降低，纤连蛋白吸附和EC粘附增加。EC粘附随着PIPAAm移植物长度的增加而减少。因此，使用表面引发的ATRP制备具有不同接枝密度和链长的PIPAAm刷表面是调节表面的温度响应性质的有效方法。
PIPAAm-brush grafted glass substrates with various graft densities and chain lengths were prepared via surface-initiated ATRP. Temperature-dependent physicochemical properties of the surfaces were characterized by means of ATR/FT-IR spectroscopy, XPS, AFM, and contact angle measurements. ATRP conditions influence the amount of grafted PIPAAm and the surface wettability and roughness of the substrate. Fibronectin adsorption and EC adhesion increased with decreasing density of PIPAAm brushes. EC adhesion was diminished with increasing PIPAAm graft length. Thus, the preparation of PIPAAm brush surface with various graft densities and chain lengths using the surface-initiated ATRP is an effective method for modulating thermo-responsive properties of surfaces.