Comparison of serum interleukin-10 (IL-10) levels between normal volunteers and patients with advanced melanoma
Comparison of serum interleukin-10 (IL-10) levels between normal volunteers and patients with advanced melanoma
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DOI：
10.1081/cnv-100102550
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发表时间：
2001-01-01
影响因子：
2.4
通讯作者：
Ando, D
中科院分区：
文献类型：
--
作者：
Nemunaitis, J;Fong, T;Ando, D
黑色素瘤是一种免疫反应性恶性肿瘤。白介素 10 (IL-10) 是一种有效的免疫抑制调节剂。本研究的目的是明确血清 IL-10 与转移性黑色素瘤患者生存的关系。对 41 名黑色素瘤患者和 50 名正常志愿者进行了分析。通过酶联免疫吸附测定 (ELISA) 测定，黑色素瘤患者的 IL-10 中位水平为 8.75 pg/ml，而
Melanoma is an immunoresponsive mnlignancy. Interleukin-10 (IL-10) is a potent regulator of immunosuppression. The purpose of this research was to define the relationship of serum IL-10 to survival in patients with metastatic melanoma. Forty-one melanoma patients and 50 normal volunteers were analyzed. The median IL-10 level as determined by enzyme-linked immunosorbent assay (ELISA) in melanoma patients was 8.75 pg/ml compared to