Rod inputs to macaque ganglion cells
Rod inputs to macaque ganglion cells
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DOI：
10.1016/s0042-6989(97)00108-9
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发表时间：
1997-10-01
期刊：
影响因子：
1.8
通讯作者：
Kremers, J
中科院分区：
文献类型：
--
作者：
Lee, BB;Smith, VC;Kremers, J
在猕猴视网膜中，在3-15度偏心范围内的视网膜位置，评估了杆输入到神经节细胞的强度。实验范式采用时间调制的异色光，其相对相位是变化的。这种模式提供了一种检测杆输入的灵敏测试。在parvocellular （PC）通路细胞中，锥体驱动信号的增益随着亮度的降低而降低，在2 td时，大约60%的细胞显示出微弱的杆状响应，即100%杆状调制时每秒几个脉冲。对于蓝色细胞，视锥驱动的反应也随着视网膜亮度的降低而降低，但没有发现rad反应。在大细胞（MC）通路细胞中，杆状细胞的输入更为明显，在20td及以下发生杆状细胞主导的反应；在较高的视网膜照度下，我们不能排除视杆侵入。即使在低视网膜照度下，反应性也保持不变。在mc通路细胞中观察到时间频率依赖的杆状锥体相互作用。杆状反应的潜伏期比锥体反应的潜伏期长，但没有证据表明杆状反应的潜伏期在细细胞和大细胞通路之间有任何差异。1997爱思唯尔科学有限公司
The strength of rod inputs to ganglion cells was assessed in the macaque retina at retinal positions within 3-15 deg eccentricity. The experimental paradigm used temporally modulated heterochromatic lights whose relative phase was varied. This paradigm provided a sensitive test to detect rod input. In parvocellular (PC) pathway cells, the gain of the cone-driven signal decreased with decrease in luminance, At 2 td a weak rod response, of a few impulses per second for 100% rod modulation, was revealed in about 60% of cells. For blue-on cells, the cone-driven response also decreased with retinal illuminance, but no rad response could be found. In magnocellular (MC) pathway cells, rod input was much more apparent, Responses became rod dominated at and below 20 td; we cannot exclude rod intrusion at higher retinal illuminances. Responsivity was maintained even at low retinal illuminances. Temporal-frequency dependent rod-cone interactions were observed in MC-pathway cells. Rod responses were of longer latency than cone responses, but there was no evidence of any difference in rod latency between parvocellular and magnocellular pathways. (C) 1997 Elsevier Science Ltd.