Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth.

Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth.
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DOI:
10.1039/c2cc36264c
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发表时间:
2012-12-07
期刊:
Chemical communications (Cambridge, England)
影响因子:
--
通讯作者:
Arifin JF
Arifin JF
中科院分区:
其他
文献类型:
--
作者:
Wang S;Wen X;Nikolovski P;Juwita V;Arifin JF

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尽管冰和核苷的晶体结构存在差异,但已证明抗冻多肽(AFP)抑制5-甲基尿苷、胞苷和肌苷的成核,并有效地改变核苷的晶体生长。AFP的分子识别库已经扩展到非冰状结晶固体。
Despite differences in the crystal structures of ice and nucleosides, antifreeze polypeptides (AFPs) have been demonstrated to inhibit nucleation of 5-methyluridine, cytidine, and inosine and modify the crystal growth of the nucleosides efficiently. The molecular recognition repertoire of AFPs has been expanded to non-ice-like crystalline solids.
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