ACUTE RESPIRATORY ILLNESS IN THE COMMUNITY - FREQUENCY OF ILLNESS AND THE AGENTS INVOLVED
ACUTE RESPIRATORY ILLNESS IN THE COMMUNITY - FREQUENCY OF ILLNESS AND THE AGENTS INVOLVED
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DOI：
10.1017/s0950268800050779
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发表时间：
1993-02-01
影响因子：
4.2
通讯作者：
SULLIVAN, KM
中科院分区：
文献类型：
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作者：
MONTO, AS;SULLIVAN, KM
对美国密歇根州特库姆塞呼吸道疾病和感染的调查分两个阶段进行，共历时11年。在第二阶段，有5363人年的观察。男性和女性的呼吸道疾病发病率在1-2岁年龄组达到高峰，此后下降。成年女性比成年男性更容易患病;职业妇女的患病率低于不外出工作的妇女。病毒的分离率随着年龄的增长而下降;鼻病毒是最常见的分离物。血清学测定的流感感染率表明，幼儿感染A型（H1N1）和B型流感相对较少。A型（H3 N2）在成年年龄组的感染率最高。分离和血清学感染率用于估计实验室程序低估每种传染源引起的呼吸道疾病比例的程度;其他研究的数据也用于这一估计。呼吸道疾病的严重程度是通过此类疾病在医生咨询中的比例来评估的。鼻病毒引起的咨询数量最多。总体而言，医生咨询与25.4%的呼吸道疾病有关。
Investigations of respiratory illnesses and infections in Tecumseh, Michigan, USA, were carried out in two phases, together covering 11 years. During the second phase, there were 5363 person-years of observation. Respiratory illness rates in both males and females peaked in the 1-2 year age group and fell thereafter. Adult females had more frequent illnesses than adult males; illnesses were less common in working women than in women not working outside the home. Isolation of viruses fell with increasing age; rhinoviruses were the most common isolate. Influenza infection rates, determined serologically, suggested relative sparing of young children from infection with type A (H1N1) and type B. Infection rates were highest in adult age groups for type A (H3N2). The isolation and serological infection rates were used to estimate the extent to which laboratory procedures underestimated the proportion of respiratory illnesses caused by each infectious agent; data from other studies were also used in this estimation. Severity of respiratory illnesses was assessed by the proportion of such illnesses that res ted in consultation of a physician. Rhinoviruses produced the greatest number of consultations. Overall, physician consultations were associated with 25.4% of respiratory illnesses.