Epidemiology and diagnosis of Mycobacterium tuberculosis in captive Asian elephants (Elephas maximus)
Epidemiology and diagnosis of Mycobacterium tuberculosis in captive Asian elephants (Elephas maximus)
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DOI：
10.1638/1042-7260(2001)032
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发表时间：
2001-03-01
影响因子：
0.7
通讯作者：
Maslow, J
中科院分区：
文献类型：
--
作者：
Mikota, SK;Peddie, L;Maslow, J
1996年8月，两头亚洲象（Elephas maximus）死亡，导致美国农业部要求对大象进行肺结核测试和治疗。1996年8月至1999年9月，6个象群的118头大象中有12头经培养证实感染结核分枝杆菌。根据M.结核病通过培养的树干清洗样本，其余（包括最初的两个）被诊断为死后。我们目前的病例历史，流行病学特征，诊断测试结果，和治疗计划，从这六个牛群。比较了皮内结核菌素试验、酶联免疫吸附试验血清学、血结核试验、核酸扩增培养等方法对结核分枝杆菌的诊断价值。大象的肺结核感染。
The deaths of two Asian elephants (Elephas maximus) in August 1996 led the United States Department of Agriculture to require the testing and treatment of elephants for tuberculosis. From August 1996 to September 1999, Mycobacterium tuberculosis infection was confirmed by culture in 12 of 118 elephants in six herds. Eight diagnoses were made antemortem on the basis of isolation of M. tuberculosis by culture of trunk wash samples', the remainder (including the initial two) were diagnosed postmortem. We present the case histories, epidemiologic characteristics, diagnostic test results, and therapeutic plans from these six herds. The intradermal tuberculin test, enzyme-linked immunosorbent assay serology, the blood tuberculosis test, and nucleic acid amplification and culture are compared as methods to diagnose M. tuberculosis infection in elephants.