Novel nonantibiotic therapies for pneumonia - Cytokines and host defense
Novel nonantibiotic therapies for pneumonia - Cytokines and host defense
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DOI：
10.1378/chest.119.2_suppl.419s
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发表时间：
2001-02-01
期刊：
影响因子：
9.6
通讯作者：
Nelson, S
中科院分区：
文献类型：
--
作者：
Nelson, S
宿主对细菌感染的有效防御依赖于吞噬细胞的激活和募集。在细菌性肺炎的情况下，这种炎症反应的启动、维持和消退依赖于细胞因子的表达。随着宿主-病原体相互作用的复杂性被进一步剖析和解开，细胞因子表达的免疫操纵将可能成为治疗严重肺部感染的重要辅助疗法。
Effective host defense against bacterial infection is dependent on the activation and recruitment of phagocytic cells. The initiation, maintenance, and resolution of this inflammatory response in the setting of bacterial pneumonia is dependent on the expression of cytokines. As the complexities of the host-pathogen interaction are further dissected and unraveled, immunologic manipulation of cytokine expression will likely become an important adjuvant therapy in the treatment of serious lung infections.