Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer
Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer
复制标题
DOI：
10.1016/j.radonc.2009.09.017
复制
发表时间：
2009-12-01
影响因子：
5.7
通讯作者：
Nutting, Christopher M.
中科院分区：
文献类型：
--
作者：
Bhide, Shreerang A.;Gulliford, Sarah;Nutting, Christopher M.
目的本研究的目的是将咽缩肌（PC）的剂量与接受同步化疗IMRT的头颈癌患者的主观和基于观察者的吞咽评估相关联。材料和方法上级缩肌（SC）的剂量体积直方图（DVHS）。对37名患者生成中缩肌（MC）和下缩肌（IC）。平均接近SC、MC和IC与客观吞咽困难等级（1年，RTOG评分）和治疗后评估的MD安德森吞咽困难量表（MDADI）的总体、总身体（TP）和身体部分（P6、P8）的最相关成分相关。吞咽困难的优势比（> 0级），整体较差（
Purpose Aim of this study was to correlate dose to pharyngeal constrictors (PC) with subjective and observer-based assessments of swallowing in patients with head and neck cancer undergoing concomitant chemo-IMRT.Materials and methods Dose-volume histograms (DVHs) for superior constrictor (SC). middle constrictor (MC) and infer tot constrictor (IC) were generated for 37 patients Mean closes to SC, MC and IC were correlated to objective dysphagia grade (1 year, RTOG scoring) and global, total physical (TP) and most relevant components of the physical section (P6, P8) of the MD Anderson dysphagia inventory (MDADI) which was evaluated post-treatment. Odds ratios of dysphagia (>grade 0), poor global (