Physical and biological properties of cyclopolymers related to DIVEMA ("pyran copolymer").
Physical and biological properties of cyclopolymers related to DIVEMA ("pyran copolymer").
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与 DIVEMA（“吡喃共聚物”）相关的环聚合物的物理和生物特性。
DOI：
10.1111/j.1749-6632.1985.tb18397.x
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发表时间：
1985
影响因子：
5.2
通讯作者：
Flick,DA
中科院分区：
文献类型：
--
作者：
Butler,GB;Xing,Y;Gifford,GE;Flick,DA
一系列结构与二乙烯基醚和马来酸酐的 1:2 交替环共聚物 (DIVEMA) 相关的共聚物已被证明具有抗肿瘤特性。讨论了这些共聚物的合成和结构，并介绍了它们作为抗肿瘤剂的有效性。某些共聚物已使用链转移剂在受控的分子量范围内制备，并且最终通过使用溶剂-非溶剂系统对所得共聚物进行分级。这些窄分子量分布的样品已被评估其抗肿瘤特性，并被发现非常有效。
A series of copolymers related in structure to the 1: 2 alternating cyclocopolymer of divinyl ether and maleic anhydride (DIVEMA) have been shown to possess antitumor properties. The synthesis and structures of these copolymers are discussed, and their effectiveness as antitumor agents is presented. Certain of the copolymers have been prepared in controlled molecular weight ranges using chain transfer agents, and the resultant copolymers finally fractionated via use of solvent-nonsolvent systems. These samples of narrow molecular weight distribution have been evaluated for their antitumor properties and have been found to be quite effective.