Computerized diagnosis of mild cognitive impairment
Computerized diagnosis of mild cognitive impairment
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DOI：
10.1016/j.jalz.2006.10.001
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发表时间：
2007-01-01
影响因子：
14
通讯作者：
Korczyn, Amos D.
中科院分区：
文献类型：
--
作者：
Aharonson, Vered;Halperin, Ilan;Korczyn, Amos D.
背景：我们之前描述了我们开发的用于轻度认知障碍（MCI）评估的软件。我们之前的研究包括一个老年非痴呆症人群的记忆投诉（n = 41），是相对同质的教育，临床病史，神经系统检查，和简易精神状态检查（MMSE）评分。在计算机化的测试中的性能模式分为两组，我们假设，一组可能有初期dementia.Methods/Results：在本研究中，我们报告了一个后续的35个科目2年后。8名被认为在基线时患有早期痴呆的受试者可以在随访中进行评估，其中6名根据MMSE和神经学家的评估已经恶化，现在已经达到痴呆的临床诊断标准。另外两个只是根据他们的计算机性能恶化。剩下的27个科目，只有一个现在符合痴呆症的临床诊断标准，虽然目前的计算机化考试确定了10个科目的表现已经恶化相比，前一届会议。结论：因此，后续检查支持我们的假设，人机交互功能可以有助于早期痴呆症的检测。(C)2007年，阿尔茨海默氏症协会。All rights reserved.
Background: We previously described software that we have developed for use in the evaluation of mild cognitive impairment (MCI). Our previous study included an aged nondemented population with memory complaints (n = 41) that was relatively homogenous in terms of education, clinical history, neurological examination, and Mini-Mental Status Examination (MMSE) scores. Performance patterns in the computerized tests separated the subjects into two groups, and we hypothesized that one group might have had incipient dementia.Methods/Results: In the present study we report a follow-up of 35 of the subjects 2 years later. Eight subjects who were thought to have incipient dementia at baseline could be evaluated in the follow-up, and six of them have deteriorated according to both MMSE and neurologists' evaluations and have now fulfilled clinical diagnostic criteria of dementia. The other two deteriorated only according to their computer performance. Of the 27 remaining subjects, only one now fulfilled clinical diagnostic criteria for dementia, although the present computerized examinations identified 10 subjects whose performance has deteriorated compared with the previous session.Conclusion: The follow-up examination thus supported our hypothesis that human-computer interaction features can contribute to the detection of incipient dementia. (C) 2007 The Alzheimer's Association. All rights reserved.