Self-report measures of medication adherence behavior: recommendations on optimal use
Self-report measures of medication adherence behavior: recommendations on optimal use
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DOI：
10.1007/s13142-015-0315-2
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发表时间：
2015-12-01
影响因子：
3.6
通讯作者：
Nilsen, Wendy J.
中科院分区：
文献类型：
--
作者：
Stirratt, Michael J.;Dunbar-Jacob, Jacqueline;Nilsen, Wendy J.
药物依从性在优化慢性疾病的许多治疗和预防方案的结果中起着重要作用。自我报告是研究和临床护理中评估依从性行为最常用的方法，但其有效性和准确性存在问题。美国国立卫生研究院依从性网络召集了一个依从性研究专家小组，研究各种慢性疾病，以审查自我报告的药物依从性措施并研究其有效性。自我报告药物依从性测量在问题措辞、回忆时间和回答项目上有很大的不同。与其他评估方法相比，自我报告倾向于高估依从性行为，并且通常具有高特异性而低敏感性。大多数证据表明，自我报告依从性措施与其他依从性措施有适度的对应关系，可以显著预测临床结果。自我报告依从性测量的质量可以通过努力使用有效的量表、评估正确的结构、改进估计、促进回忆、减少社会期望偏差和采用技术交付来提高。自我报告药物依从性措施可以提供可操作的信息，尽管其局限性。当需要速度、效率和低成本的措施时，如在临床护理中经常出现的情况，它们是首选。
Medication adherence plays an important role in optimizing the outcomes of many treatment and preventive regimens in chronic illness. Self-report is the most common method for assessing adherence behavior in research and clinical care, but there are questions about its validity and precision. The NIH Adherence Network assembled a panel of adherence research experts working across various chronic illnesses to review self-report medication adherence measures and research on their validity. Self-report medication adherence measures vary substantially in their question phrasing, recall periods, and response items. Self-reports tend to overestimate adherence behavior compared with other assessment methods and generally have high specificity but low sensitivity. Most evidence indicates that self-report adherence measures show moderate correspondence to other adherence measures and can significantly predict clinical outcomes. The quality of self-report adherence measures may be enhanced through efforts to use validated scales, assess the proper construct, improve estimation, facilitate recall, reduce social desirability bias, and employ technologic delivery. Self-report medication adherence measures can provide actionable information despite their limitations. They are preferred when speed, efficiency, and low-cost measures are required, as is often the case in clinical care.