PREVALENCE AND GENESIS OF ENDOMETRIOSIS
PREVALENCE AND GENESIS OF ENDOMETRIOSIS
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DOI：
10.1093/oxfordjournals.humrep.a137377
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发表时间：
1991-04-01
影响因子：
6.1
通讯作者：
TEMPLETON, A
中科院分区：
文献类型：
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作者：
MAHMOOD, TA;TEMPLETON, A
一组1542绝经前白人妇女进行了前瞻性评估，调查子宫内膜异位症的患病率。 这些妇女因不孕症（n = 654）接受腹腔镜检查，接受腹腔镜绝育（n = 598），因慢性腹痛和盆腔痛（n = 156）接受腹腔镜检查或因功能失调性子宫出血（n = 134）接受腹式子宫切除术。 子宫内膜异位症在接受不孕症调查的妇女中（21%）比接受绝育手术的妇女（6%）更常见。 在那些被调查的慢性腹痛，子宫内膜异位症的发病率为15%，而在那些接受腹式子宫切除术，这是25%。 在所有组中，盆腔正常的患者联合使用避孕药的总时间明显高于子宫内膜异位症患者。 这表明，在易受影响的妇女，无论是生育和不孕，一个长期的定期自发月经可能发挥了致病作用，在子宫内膜异位症的发生。
A group of 1542 pre-menopausal Caucasian women were assessed prospectively to investigate the prevalence of endometriosis. The women were either having laparoscopy because of infertility (n = 654), undergoing laparoscopic sterilization (n = 598), having laparoscopy because of chronic abdominal and pelvic pain (n = 156) or undergoing abdominal hysterectomy for dysfunctional uterine bleeding (n = 134). Endometriosis was noted more frequently among women being investigated for infertility (21%) than among those undergoing sterilization (6%). Among those being investigated for chronic abdominal pain, the incidence of endometriosis was 15%, while among those undergoing abdominal hysterectomy, it was 25%. In all groups the total duration of combined pill usage was significantly higher in patients who had a normal pelvis compared to those with endometriosis. It is suggested that among susceptible women, both fertile and infertile, a prolonged period of regular spontaneous menstruation may play a causative role in the genesis of endometriosis.