Sodium hyaluronate in the treatment of keratoconjunctivitis sicca

Sodium hyaluronate in the treatment of keratoconjunctivitis sicca
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玻璃酸钠治疗干燥性角结膜炎

DOI:
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发表时间:
1989
影响因子:
3.4
通讯作者:
M. Norn
M. Norn
中科院分区:
医学3区
文献类型:
--
作者:
B. Sand;K. Marner;M. Norn

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抽象的。在一项双盲交叉试验中评估了透明质酸钠滴眼液治疗严重干燥性角结膜炎 (KCS) 的效果,比较了 20 名患者中 0.1% 溶液、0.2% 溶液和安慰剂的效果。我们发现与安慰剂相比,0.2% 治疗后孟加拉玫瑰染色显着减少,破裂时间增加。 Schirmer 值和角膜敏感性没有发现显着差异。患者明显偏好透明质酸钠治疗。我们的结论是,透明质酸钠滴眼液似乎是治疗 KCS 的一种有价值的新药物。
Abstract. The effect of sodium hyaluronate eye drops in the treatment of severe keratoconjunctivitis sicca (KCS) was evaluated in a double masked crossover trial, comparing the effect of a 0.1% solution, a 0.2% solution and placebo in 20 patients. We found significantly decreased rose bengal staining and increased break‐up time following 0.2% treatment compared to placebo. No significant difference was found in the Schirmer values and the cornea sensitivity. The patients significantly preferred sodium hyaluronate treatment. We conclude that sodium hyaluronate eye drops seem to be a valuable new agent in the management of KCS.
DOI: 10.1016/s0140-6736(74)90884-8
发表时间: 1974-01-01
期刊: LANCET
影响因子: 168.9
作者:
HUSKISSON, EC
通讯作者: HUSKISSON, EC